Compare Benzamycin vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benzamycin
(benzoyl peroxide / erythromycin)

Solodyn
(minocycline)

Topical treatment for acne. Benzamycin (Benzoyl Peroxide / Erythromycin) is a topical combination acne treatment that may work better for people who didn't see an improvement when taking either medicine alone or simply don't want to take pill medication. You need to be careful because it can bleach your hair, clothing and other fabrics. It also needs to be stored in the refrigerator and is only good for three months..Treats bacterial infections. Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.53Benzamycin
Reviews for Benzamycin
54%
of people (All ages) say Benzamycin is worth it
26%
say it works well
12%
say it's a big hassle
146 reviews
Have you used Benzamycin (benzoyl peroxide / erythromycin)?
Worth itNot sureNot worth it
Reviews for Minocycline
53%
+1% better vs. Benzamycin
59%
-33% worse vs. Benzamycin
18%
+6% better vs. Benzamycin
Have you used Solodyn (minocycline)?
Worth itNot sureNot worth it
Side effects
BenzamycinMinocycline
  • Dyness 3%
  • Urticarial reaction 3%
More Benzamycin side effects »

We haven’t found good data for Minocycline side effects.

FDA side effect reports for Minocycline »
How it works
BenzamycinMinocycline
Benzamycin (Benzoyl Peroxide / Erythromycin) is a combination topical medicine. Erythromycin (an antibiotic) kills bacteria that cause acne. Benzoyl peroxide works to fight the bacteria and shed acne-affected skin.Solodyn (Minocycline) is a tetracycline antibiotic. It stops bacteria by preventing them from reproducing and repairing themselves.
Type of medication
BenzamycinMinocycline
Prescription onlyPrescription only
Available as
BenzamycinMinocycline
  • Cream, gel, or ointment
  • Pill
  • Extended release
  • Extended release capsule
Used for
BenzamycinMinocycline
Risk factors for serious side effects
BenzamycinMinocycline
  • Using other medicines or products that irritate the skin
  • Eczema
  • Extreme temperatures (hot or cold)
  • Long-term use of Benzamycin (Benzoyl Peroxide / Erythromycin)
Detailed Benzamycin (benzoyl peroxide / erythromycin) risks & warnings »
  • Age 8 years or younger
  • Using oral birth control pills
  • Long antibiotic treatment period
  • Women of childbearing age
Detailed Solodyn (minocycline) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Price
BenzamycinMinocycline
No price related info.
  • Available as a generic, so it should be reasonably priced.
Pain
BenzamycinMinocycline
  • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
No pain related info.
Weight
BenzamycinMinocycline
  • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
No weight related info.
Upsides and benefits
BenzamycinMinocycline
  • Benzamycin works better to reduce bacteria in oil glands and improve overall signs and symptoms of acne than either medicine alone.
  • Reduces bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
  • Combining an antibiotic with benzoyl peroxide lowers the chances of Benzamycin not working as well over time.
  • Although Benzamycin can irritate the skin, a true skin allergy is rare.
  • Can be used in combination with acne pill medicine if your doctor thinks you need it.
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
Downsides and risks
BenzamycinMinocycline
  • There's a risk of irritation with anything you apply to your skin and this is no different. Benzamycin, contains a topical antibiotic and can cause redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
  • Can cause severe inflammation of the large intestine (pseudomembranous colitis).
  • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
  • Can cause bleaching of hair and clothing.
  • You'll need to stay out of the sun or apply a sunscreen if you go outdoors.
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
Tips from our pharmacists for people taking the medication
BenzamycinMinocycline
  • Combination medicine you apply to your skin to treat acne.
  • Apply a thin film to clean and dry affected skin twice a day- in the morning and evening.
  • Store in the refrigerator, but don't freeze.
  • The pharmacist mixes the medicine when you pick it up at the drugstore. You'll need to use it within three months of this date or dispose of it properly.
  • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
  • Using a moisturizer that doesn't block your pores (non-comedogenic) may help lessen common side effects of skin dryness and peeling.
  • Taking good care of your skin is an important part of treating acne. Lightly wash with warm water and non-soap-based or gentle cleanser.
  • Both men and women should use barrier methods of birth control while on Solodyn (Minocycline) since it can cause birth defects and make birth control pills less effective.
  • Can make you dizzy, so be careful if you're getting up from lying down or sitting. Don't drive until you know how it affects you.
  • Can stain your teeth, tongue and gums, but this is temporary.
  • Take this exactly how your doctor or pharmacist tells you until it's all gone.
  • Don't eat any dairy products or take any vitamins within 2 hours of taking Solodyn (Minocycline) because they can make the medication less effective.
Learn more
More about BenzamycinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Benzamycin (benzoyl peroxide / erythromycin)?
Worth itNot sureNot worth it
More about MinocyclineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Solodyn (minocycline)?
Worth itNot sureNot worth it