Compare Benzamycin vs. Renova

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benzamycin
(Benzoyl Peroxide / Erythromycin)

Renova
(Tretinoin)

Topical treatment for acne. Benzamycin (Benzoyl Peroxide / Erythromycin) is a topical combination acne treatment that may work better for people who didn't see an improvement when taking either medicine alone or simply don't want to take pill medication. You need to be careful because it can bleach your hair, clothing and other fabrics. It also needs to be stored in the refrigerator and is only good for three months..Treats acne and sun damage. Renova (Tretinoin) isn't a cure for fine lines and wrinkles, but it's clinically proven to improve them.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.527397260273973Benzamycin
Reviews for Benzamycin (Benzoyl Peroxide / Erythromycin)
54%
of people say Benzamycin (Benzoyl Peroxide / Erythromycin) is worth it
26%
say it works well
12%
say it's a big hassle
Reviews for Renova (Tretinoin)
40%
14% vs. Benzamycin (Benzoyl Peroxide / Erythromycin)
26%
Same vs. Benzamycin (Benzoyl Peroxide / Erythromycin)
28%
16% vs. Benzamycin (Benzoyl Peroxide / Erythromycin)
Side effects
BenzamycinRenova

The Benzamycin FDA package insert doesn’t have numbers about how common side effects are.

More about Benzamycin side effects »
  • Severe local irritation 6%
More Renova side effects »
How it works
BenzamycinRenova
Benzamycin (Benzoyl Peroxide / Erythromycin) is a combination topical medicine. Erythromycin (an antibiotic) kills bacteria that cause acne. Benzoyl peroxide works to fight the bacteria and shed acne-affected skin.Renova (Tretinoin) is a vitamin A derivative. Researchers don't know exactly how it works, but it seems to make skin cells renew faster and better.
Type of medication
BenzamycinRenova
Acne agent
Antibiotic
Prescription only
Acne agent
Retinoid
Prescription only
Available as
BenzamycinRenova
  • Cream, gel, or ointment
  • Cream, gel, or ointment
Used for (click to learn more)
BenzamycinRenova
Risk factors for serious side effects
BenzamycinRenova
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
      • Long-term use of Benzamycin (Benzoyl Peroxide / Erythromycin)
      Detailed Benzamycin (Benzoyl Peroxide / Erythromycin) risks & warnings »
      • Using other medicines or products that irritate the skin
      • Eczema
      • Extreme temperatures (hot or cold)
        • Allergy to fish or fish products
          Detailed Renova (Tretinoin) risks & warnings »
          Pregnancy category
          BenzamycinRenova
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
          No specific weight-related info.
          Upsides and benefits
          BenzamycinRenova
          • Benzamycin works better to reduce bacteria in oil glands and improve overall signs and symptoms of acne than either medicine alone.
          • Reduces bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
          • Combining an antibiotic with benzoyl peroxide lowers the chances of Benzamycin not working as well over time.
          • Although Benzamycin can irritate the skin, a true skin allergy is rare.
          • Can be used in combination with acne pill medicine if your doctor thinks you need it.
          • You only need to apply it once a day, usually in the evening.
          • Most people who reported having skin irritation said that it was mild.
          • Part of a complete program to help you take better care of your skin.
          Downsides and risks
          BenzamycinRenova
          • There's a risk of irritation with anything you apply to your skin and this is no different. Benzamycin, contains a topical antibiotic and can cause redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
          • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
          • Can cause severe inflammation of the large intestine (pseudomembranous colitis).
          • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
          • Can cause bleaching of hair and clothing.
          • You'll need to stay out of the sun or apply a sunscreen if you go outdoors.
          • It may take up to 6 months to see the full benefit for facial wrinkles.
          • Not a good choice for women who want to become or are pregnant
          • Can change the color and texture of your skin if used long-term.
          • You need to be careful about avoiding any sunlight or artificial tanning while using it.
          • It doesn't work for deep wrinkles.
          Tips from our pharmacists for people taking the medication
          BenzamycinRenova
          • Combination medicine you apply to your skin to treat acne.
          • Apply a thin film to clean and dry affected skin twice a day- in the morning and evening.
          • Store in the refrigerator, but don't freeze.
          • The pharmacist mixes the medicine when you pick it up at the drugstore. You'll need to use it within three months of this date or dispose of it properly.
          • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
          • Using a moisturizer that doesn't block your pores (non-comedogenic) may help lessen common side effects of skin dryness and peeling.
          • Taking good care of your skin is an important part of treating acne. Lightly wash with warm water and non-soap-based or gentle cleanser.
          • Works best as part of a complete skin care program (including SPF) to protect your skin from sun damage.
          • Renova doesn't permanently erase or improve significant skin changes such as deep wrinkles.
          • Apply a very small amount (pea-size) on entire face once a day at bedtime.
          • You'll need to use Renova regularly for at least 3 to 4 months before you see improvement. Once you stop, the improvement may slowly disappear.
          • Renova wasn't studied in people with skin cancer or serious damage from the sun (actinic keratosis) so it's not known if this would benefit.
          • Not safe to use during pregnancy. Even though Renova is applied to the skin, a small amount is absorbed and harmful to your unborn baby.
          • Some medicines you take by mouth can make you more sensitive to sunlight and combine with effects of Renova. Check with your doctor or pharmacist before you take any new medicines.
          Learn more
          More about BenzamycinSide effectsReviews & ratingsAlternativesFDA package insert
          More about RenovaSide effectsReviews & ratingsFDA package insert