Compare Benzoyl Peroxide vs. Benzamycin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benzac (Benzoyl Peroxide)

Prescription or OTC
Topical treatment for acne and skin wounds.

Benzac (Benzoyl Peroxide) is a very popular topical acne treatment you can get over-the-counter or by prescription that may be better for people who don't want to take pill medication. Just be careful because it can bleach your hair, clothing and other fabrics.

4.6/ 7 average rating with 394 reviewsforBenzoyl Peroxide
Topical treatment for acne.

Benzamycin (Benzoyl Peroxide / Erythromycin) is a topical combination acne treatment that may work better for people who didn't see an improvement when taking either medicine alone or simply don't want to take pill medication. You need to be careful because it can bleach your hair, clothing and other fabrics. It also needs to be stored in the refrigerator and is only good for three months..

4.5/ 7 average rating with 146 reviewsforBenzamycin
Upsides
  • Benzoyl peroxide is used to reduce bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
  • Helps stop blemishes from forming when oil and skin cells become trapped in pores.
  • Although Benzoyl peroxide can irritate the skin, a true skin allergy is rare.
  • Can be used in combination with acne pill medicine if your doctor thinks you need it.
  • It's available in non-prescription strengths, easy to buy at any drugstore and pretty cheap compared to prescription pills to treat your acne.
  • Benzamycin works better to reduce bacteria in oil glands and improve overall signs and symptoms of acne than either medicine alone.
  • Reduces bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
  • Combining an antibiotic with benzoyl peroxide lowers the chances of Benzamycin not working as well over time.
  • Although Benzamycin can irritate the skin, a true skin allergy is rare.
  • Can be used in combination with acne pill medicine if your doctor thinks you need it.
Downsides
  • Higher strengths (concentrations) can cause skin irritation and may appear as redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas.
  • Not the best choice if you're pregnant. Benzoyl peroxide is categorized as pregnancy Category C (weigh risks vs benefits) as compared to similar topical medicines that are in Category B (likely safe).
  • Can cause bleaching of hair and clothing.
  • May not work as well when used by itself over long period of time.
  • You'll need to stay out of the sun or apply a sunscreen if you have to be outdoors.
  • There's a risk of irritation with anything you apply to your skin and this is no different. Benzamycin, contains a topical antibiotic and can cause redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
  • Can cause severe inflammation of the large intestine (pseudomembranous colitis).
  • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
  • Can cause bleaching of hair and clothing.
  • You'll need to stay out of the sun or apply a sunscreen if you go outdoors.
Used for
Dosage forms
  • Cream, gel, or ointment
  • Lotion
  • Liquid
  • Topical solution
  • Cream, gel, or ointment
Price
No pricing information available
Lowest price near you
$480.14
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Reviews
394 
60%
think this treatment is worth it
29%
think this treatment works well
9%
think this treatment is a hassle

Have you used Benzac (Benzoyl Peroxide)?

Leave a review
146 
54%
think this treatment is worth it
26%
think this treatment works well
12%
think this treatment is a hassle

Have you used Benzamycin (Benzoyl Peroxide / Erythromycin)?

Leave a review
Side effects
The Benzac (Benzoyl Peroxide) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Dyness
    3%
  • Urticarial reaction
    3%
See more detailed side effects
Risks and warnings
  • Skin irritation

    Using other medicines or products that irritate the skin

    ...and 2 more risk factors

See more detailed risks and warnings
  • Skin irritation

    Using other medicines or products that irritate the skin

    ...and 2 more risk factors

  • Development of more serious infections

    Long-term use of Benzamycin (Benzoyl Peroxide / Erythromycin)

See more detailed risks and warnings