Compare Betaseron vs. Copaxone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Copaxone (Glatiramer)

Prescription only
Lowers the frequency of MS exacerbations.

Betaseron (Interferon Beta-1B) is an injectable medicine effective for relapsing, remitting MS with fewer side effects and every other day dosing.

3.5/ 5 average rating with 21 reviewsforBetaseron
Lowers the frequency of multiple sclerosis exacerbations.

Copaxone (Glatiramer) is an injectable medicine that's effective for relapsing, remitting MS. It has fewer side effects than other meds, but the self-injections are needed frequently.

3.2/ 5 average rating with 30 reviewsforCopaxone
Upsides
  • Interferon beta-1b was the first disease modifying agent for MS approved by the FDA to treat relapsing-remitting multiple sclerosis (RRMS).
  • In short and long-term follow-up studies, Interferon beta-1b was shown to slow MS progression, reduce the number of flair-ups and increase overall survival.
  • Convenient every-other-day dosing and refrigeration-free storage (before mixing) is less of a hassle.
  • Interferon beta-1b has been shown to be more effective than Avonex in reducing new lesions, which lowers relapse and disease progression in people with RRMS.
  • May be a treatment option for people with secondary progressive multiple sclerosis (SPMS).
  • One of the main treatments for relapsing multiple sclerosis (MS) that has been around for many years.
  • Helps reduce the frequency of MS relapse episodes.
  • Fewer side effects than other injectable MS medicines, like interferons.
  • Can be helpful in maintaining nerve functions.
  • Likely safe to use during pregnancy.
  • Copaxone (Glatiramer) is a possible treatment for primary-progressive MS (PPMS) even though the clinical evidence is not conclusive (there are currently no approved treatments for PPMS).
Downsides
  • Requires injections.
  • Injection site reactions are common. Symptoms range from pain, redness, and swelling to severe reactions with skin death around the injection site.
  • Flu-like symptoms are common after interferon injections, but are less likely with Interferon beta-1b in particular.
  • Blood testing required before and during use based on your other conditions.
  • Unclear consequences to fetus during pregnancy.
  • Requires injections, either day or every other day (but no more than three times a week), depending on the dose you're taking.
  • Injection site reactions are common with pain, redness, swelling, and lipoatrophy (loss of fat under the skin where the injection is made).
  • Doesn't stop the progression of MS.
Used for
Dosage forms
  • Injection
  • Injection
Price
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$6073.22
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Reviews
21 reviews so far
57%
saidit'sworth it
48%
saiditworked well
38%
saidit'sa big hassle

Have you used Betaseron (Interferon Beta-1B)?

Leave a review
30 reviews so far
50%
saidit'sworth it
37%
saiditworked well
27%
saidit'sa big hassle

Have you used Copaxone (Glatiramer)?

Leave a review
Side effects
49possible side effects
  • Lymphocytes count decreased (<1500/mm3)
    66%
  • Asthenia
    48%
  • Immunogenicity
    45%
  • Headache
    43%
  • Flu-like symptoms (complex)
    37%
  • Pain
    35%
  • Hypertonia
    33%
  • Injection site reaction
    26%
  • Fever
    19%
  • Leukopenia
    18%
  • Insomnia
    16%
  • Incoordination
    15%
  • Rash
    15%
  • Myalgia
    14%
  • Abdominal pain
    11%
  • Peripheral edema
    10%
  • Chills
    9%
  • Skin disorder
    8%
  • Urinary urgency
    8%
  • Metrorrhagia
    7%
  • Impotence
    6%
  • Chest pain
    6%
  • Absolute neutrophil count decreased (< 1500/mm3)
    5%
  • White blood cell count decreased (<3000/mm3)
    4%
  • Hypertension
    4%
  • Alanine aminotransferase increased (SGPT > 5X baseline)
    4%
  • Lymphadenopathy
    3%
  • Dyspnea
    3%
  • Malaise
    3%
  • Alopecia
    2%
  • Anxiety
    2%
  • Arthralgia
    2%
  • Constipation
    2%
  • Diarrhea
    2%
  • Dizziness
    2%
  • Dyspepsia
    2%
  • Dysmenorrhea
    2%
  • Leg cramps
    2%
  • Menorrhagia
    2%
  • Myasthenia
    2%
  • Nausea
    2%
  • Nervousness
    2%
  • Palpitations
    2%
  • Peripheral vascular disorder
    2%
  • Prostatic disorder
    2%
  • Tachycardia
    2%
  • Urinary frequency
    2%
  • Vasodilatation
    2%
  • Weight increase
    2%
See more detailed side effects
The Copaxone (Glatiramer) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver damage
    • Alcohol use
    • Taking drugs that are liver toxic
    • Active or history of liver disease
  • Serious allergic reactions
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Heart problems
    • History of or current heart disease
  • Flu-like symptom complex
  • Harm to fetus
    • Women of childbearing age
  • Injection site reaction
    • Not changing injection sites
  • Blood cell problems
    • Bone marrow suppression
  • Albumin in the product
See more detailed risks and warnings
  • Injection reaction
  • Skin damage
  • Chest pain
  • Immunosuppression
  • Risk to fetus
See more detailed risks and warnings