Compare Bisoprolol vs. Catapres

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zebeta
(Bisoprolol)

Catapres
(Clonidine)

Lowers blood pressure. Zebeta (Bisoprolol) is usually given to people who have taken other blood pressure meds unsuccessfully or have recently had significant heart problems.Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.
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Reviews & ratings
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Reviews for Catapres (Clonidine)
42%
31% vs. Zebeta (Bisoprolol)
33%
31% vs. Zebeta (Bisoprolol)
34%
7% vs. Zebeta (Bisoprolol)
Side effects
BisoprololCatapres

We haven’t found good data for Bisoprolol side effects.

FDA side effect reports for Bisoprolol »

The Catapres FDA package insert doesn’t have numbers about how common side effects are.

More about Catapres side effects »
How it works
BisoprololCatapres
Zebeta (Bisoprolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it work less to pump.Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.
Type of medication
BisoprololCatapres
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Alpha agonist
Prescription only
Available as
BisoprololCatapres
  • Pill
  • Pill
  • Extended release
  • Patch
Used for (click to learn more)
BisoprololCatapres
Risk factors for serious side effects
BisoprololCatapres
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    Detailed Zebeta (Bisoprolol) risks & warnings »
    • Sudden discontinuation of medicine
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
    Detailed Catapres (Clonidine) risks & warnings »
    Pregnancy category
    BisoprololCatapres
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    BisoprololCatapres
    • Good for protecting the heart and lowering blood pressure if you've had a heart attack.
    • Available in a generic version.
    • Also comes in combination with other medications to lower blood pressure.
    • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
    • Available in a weekly patch for people that aren't good at taking medicine by mouth.
    • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
    • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
    Downsides and risks
    BisoprololCatapres
    • This isn't a first choice medication to lower blood pressure.
    • You can't stop taking it suddenly, or else you're more likely to have a heart attack or other problems with your heart.
    • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
    • The pill form can make some people sleepy, dizzy, and have dry mouth.
    • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    Tips from our pharmacists for people taking the medication
    BisoprololCatapres
    • Zebeta (Bisoprolol) can make you feel dizzy the first few days you take it, so be careful driving and quickly standing up until you know how your body reacts to it.
    • Don't stop taking it suddenly without talking to your doctor.
    • If you have diabetes, Zebeta (Bisoprolol) can make it difficult to tell if your blood sugar is low.
    • Can cause headache, fatigue, and make you more likely to get colds or the flu.
    • Usually taken together with other medicines for better blood pressure control.
    • Can cause drowsiness, headache, dizziness, and dry mouth.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • If side effects don't go away, talk to your doctor about alternatives.
    • The weekly patch form can have fewer side effects.
    • Don't stop taking this medicine suddenly.
    • Extended release tablet also used to treat ADHD.
    Learn more
    More about BisoprololSide effectsReviews & ratingsAlternativesFDA package insert
    More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert