Compare Bisoprolol vs. Catapres

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zebeta
(bisoprolol)

Catapres
(clonidine)

Lowers blood pressure. Zebeta (Bisoprolol) is usually given to people who have taken other blood pressure meds unsuccessfully or have recently had significant heart problems.Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.44Bisoprolol
Reviews for Bisoprolol
67%
of people (All ages) say Bisoprolol is worth it
61%
say it works well
28%
say it's a big hassle
Have you used Zebeta (bisoprolol)?
Worth itNot sureNot worth it
Reviews for Catapres
42%
+25% better vs. Bisoprolol
33%
+28% better vs. Bisoprolol
35%
+7% better vs. Bisoprolol
Have you used Catapres (clonidine)?
Worth itNot sureNot worth it
Side effects
BisoprololCatapres

We haven’t found good data for Bisoprolol side effects.

FDA side effect reports for Bisoprolol »
  • Redness/itching / pruritis 26%
  • Dry mouth 25%
  • Drowsiness 12%
  • Skin blistering 7%
  • Fatigue 6%
  • Headache 5%
  • Skin or nail darkening 5%
  • Allergic contact sensitization 5%
  • Burning 3%
  • Lack of energy 3%
More Catapres side effects »
How it works
BisoprololCatapres
Zebeta (Bisoprolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it work less to pump.Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.
Type of medication
BisoprololCatapres
Prescription onlyPrescription only
Available as
BisoprololCatapres
  • Pill
  • Pill
  • Extended release
  • Patch
Used for
BisoprololCatapres
Risk factors for serious side effects
BisoprololCatapres
  • Diabetes
  • Coronary artery disease
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Zebeta (bisoprolol) risks & warnings »
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Catapres (clonidine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Sleep
BisoprololCatapres
No sleep related info.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
Upsides and benefits
BisoprololCatapres
  • Good for protecting the heart and lowering blood pressure if you've had a heart attack.
  • Available in a generic version.
  • Also comes in combination with other medications to lower blood pressure.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
Downsides and risks
BisoprololCatapres
  • This isn't a first choice medication to lower blood pressure.
  • You can't stop taking it suddenly, or else you're more likely to have a heart attack or other problems with your heart.
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
BisoprololCatapres
  • Zebeta (Bisoprolol) can make you feel dizzy the first few days you take it, so be careful driving and quickly standing up until you know how your body reacts to it.
  • Don't stop taking it suddenly without talking to your doctor.
  • If you have diabetes, Zebeta (Bisoprolol) can make it difficult to tell if your blood sugar is low.
  • Can cause headache, fatigue, and make you more likely to get colds or the flu.
  • Usually taken together with other medicines for better blood pressure control.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • The weekly patch form can have fewer side effects.
  • Don't stop taking this medicine suddenly.
  • Extended release tablet also used to treat ADHD.
Learn more
More about BisoprololSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zebeta (bisoprolol)?
Worth itNot sureNot worth it
More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Catapres (clonidine)?
Worth itNot sureNot worth it