Compare Brotapp vs. Benadryl

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Brotapp
(pseudoephedrine / brompheniramine)

Benadryl
(diphenhydramine)

Relieves congestion and allergy symptoms. Brotapp (Pseudoephedrine / Brompheniramine) is okay for treating congestion, but it could make you really tired or keep you wide awake.Treats allergy symptoms and helps you sleep. Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.
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Best available price for 30 (25mg) capsules of diphenhydramine
Reviews & ratings
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Reviews for Brotapp (pseudoephedrine / brompheniramine)
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of people (All ages) say Brotapp (pseudoephedrine / brompheniramine) is worth it
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say it works well
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say it's a big hassle
Have you used Brotapp (pseudoephedrine / brompheniramine)?
Worth itNot sureNot worth it
Reviews for Benadryl (diphenhydramine)
86%
+86% better vs. Brotapp (pseudoephedrine / brompheniramine)
59%
+59% better vs. Brotapp (pseudoephedrine / brompheniramine)
8%
-8% worse vs. Brotapp (pseudoephedrine / brompheniramine)
294 reviews
Have you used Benadryl (diphenhydramine)?
Worth itNot sureNot worth it
Side effects
BrotappBenadryl

We haven’t found good data for Brotapp side effects.

FDA side effect reports for Brotapp »

We haven’t found good data for Benadryl side effects.

FDA side effect reports for Benadryl »
How it works
BrotappBenadryl
Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves allergy and cold symptoms. Brompheniramine (an antihistamine) treats runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Benadryl (Diphenhydramine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. It also makes you sleepy.
Type of medication
BrotappBenadryl
Over-the-counter
Prescription or OTC
Available as
BrotappBenadryl
  • Pill
  • Liquid
  • Pill
  • Oral solution
  • Cream, gel, or ointment
Used for
BrotappBenadryl
Risk factors for serious side effects
BrotappBenadryl
  • Taking with alcohol
  • Taking other medicines that make you drowsy or less alert
  • Women of childbearing age
  • History of high blood pressure
  • Taking MAO inhibitors
Detailed Brotapp (pseudoephedrine / brompheniramine) risks & warnings »
  • Using other drugs with the same ingredients
  • Age 65 years or older
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Children age 6 years and younger
Detailed Benadryl (diphenhydramine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Alcohol
BrotappBenadryl
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Don't take it with alcohol or other drugs that make you sleepy.
Sleep
BrotappBenadryl
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
Upsides and benefits
BrotappBenadryl
  • Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves cold and allergy symptoms. It's good to use if you have congestion, watery eyes, and sneezing.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
  • Brompheniramine (an antihistamine) helps relieve itchy eyes, runny nose, and sneezing.
  • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It makes you sleepy, so it'll help if your allergies are bothering you at night.
  • The effects wear off in 4 to 6 hours, so side effects don't last that long.
  • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
Downsides and risks
BrotappBenadryl
  • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • Pseudoephedrine (the decongestant) can make your heart race or make you feel anxious and restless.
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • The two ingredients in this medication can make you either really tired or keep you wide awake. See how it affects you before doing anything important.
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
  • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
  • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
  • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
Tips from our pharmacists for people taking the medication
BrotappBenadryl
  • Brompheniramine (the antihistamine ingredient in Brotapp (Pseudoephedrine / Brompheniramine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Pseudoephedrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
  • You need to show an ID to buy Brotapp (Pseudoephedrine / Brompheniramine) in the drugstore because it contains pseudoephedrine.
  • Take it as needed every 4 to 6 hours.
  • Benadryl (Diphenhydramine) can make you dehydrated, so avoid this side effect by drinking plenty of fluids.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • Don't take it with alcohol or other drugs that make you sleepy.
  • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
  • If you only have itchy or watery eyes, try using just an antihistamine eye drop.
Learn more
More about BrotappSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Brotapp (pseudoephedrine / brompheniramine)?
Worth itNot sureNot worth it
More about BenadrylSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Benadryl (diphenhydramine)?
Worth itNot sureNot worth it