Compare Brotapp vs. Benadryl

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Brotapp
(Pseudoephedrine / Brompheniramine)

Benadryl
(Diphenhydramine)

Relieves congestion and allergy symptoms. Brotapp (Pseudoephedrine / Brompheniramine) is okay for treating congestion, but it could make you really tired or keep you wide awake.Treats allergy symptoms and helps you sleep. Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.
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Reviews & ratings
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Reviews for Benadryl (Diphenhydramine)
85%
+85% vs. Brotapp (Pseudoephedrine / Brompheniramine)
57%
+57% vs. Brotapp (Pseudoephedrine / Brompheniramine)
8%
8% vs. Brotapp (Pseudoephedrine / Brompheniramine)
Side effects
BrotappBenadryl

We haven’t found good data for Brotapp side effects.

FDA side effect reports for Brotapp »

We haven’t found good data for Benadryl side effects.

FDA side effect reports for Benadryl »
How it works
BrotappBenadryl
Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves allergy and cold symptoms. Brompheniramine (an antihistamine) treats runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Benadryl (Diphenhydramine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. It also makes you sleepy.
Type of medication
BrotappBenadryl
DecongestantAntihistamine
1st generation
Over-the-counter
Antihistamine
1st generation
Prescription or OTC
Available as
BrotappBenadryl
  • Pill
  • Liquid
  • Pill
  • Oral solution
  • Cream, gel, or ointment
Used for (click to learn more)
BrotappBenadryl
Risk factors for serious side effects
BrotappBenadryl
  • Taking with alcohol
  • Taking other medicines that make you drowsy or less alert
  • Women of childbearing age
  • History of high blood pressure
  • Taking MAO inhibitors
  • Age 65 years or older
  • Glaucoma
  • Benign prostatic hypertrophy (BPH)
Detailed Brotapp (Pseudoephedrine / Brompheniramine) risks & warnings »
  • Using other drugs with the same ingredients
  • Age 65 years or older
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Children age 6 years and younger
  • Enlarged prostate
  • History of bladder problems
  • Glaucoma
  • Nursing mothers
Detailed Benadryl (Diphenhydramine) risks & warnings »
Pregnancy category
BrotappBenadryl
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
Alcohol
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Don't take it with alcohol or other drugs that make you sleepy.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Brotapp (Pseudoephedrine / Brompheniramine) can make you drowsy and lower your ability to focus, think, and react. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • People age 65 years and older have a higher risk of side effects from taking antihistamine medications like Benadryl (Diphenhydramine). Watch for changes in vision, severe dry mouth, trouble urinating, or constipation. The drowsiness caused by Benadryl (Diphenhydramine) can make you "unsteady" on your feet, leading to a higher chance of falls.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
BrotappBenadryl
  • Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves cold and allergy symptoms. It's good to use if you have congestion, watery eyes, and sneezing.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
  • Brompheniramine (an antihistamine) helps relieve itchy eyes, runny nose, and sneezing.
  • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It makes you sleepy, so it'll help if your allergies are bothering you at night.
  • The effects wear off in 4 to 6 hours, so side effects don't last that long.
  • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
Downsides and risks
BrotappBenadryl
  • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • Pseudoephedrine (the decongestant) can make your heart race or make you feel anxious and restless.
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • The two ingredients in this medication can make you either really tired or keep you wide awake. See how it affects you before doing anything important.
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
  • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
  • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
  • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
Tips from our pharmacists for people taking the medication
BrotappBenadryl
  • Brompheniramine (the antihistamine ingredient in Brotapp (Pseudoephedrine / Brompheniramine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Pseudoephedrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
  • You need to show an ID to buy Brotapp (Pseudoephedrine / Brompheniramine) in the drugstore because it contains pseudoephedrine.
  • Take it as needed every 4 to 6 hours.
  • Benadryl (Diphenhydramine) can make you dehydrated, so avoid this side effect by drinking plenty of fluids.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • Don't take it with alcohol or other drugs that make you sleepy.
  • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
  • If you only have itchy or watery eyes, try using just an antihistamine eye drop.
Learn more
More about BrotappSide effectsReviews & ratingsAlternativesFDA package insert
More about BenadrylSide effectsReviews & ratingsAlternativesFDA package insert