Brotapp vs. Flonase

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(Pseudoephedrine / Brompheniramine)


Relieves congestion and allergy symptoms. Brotapp (Pseudoephedrine / Brompheniramine) is okay for treating congestion, but it could make you really tired or keep you wide awake.Relieves allergy symptoms. Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.
How it works
Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves allergy and cold symptoms. Brompheniramine (an antihistamine) treats runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Flonase (Fluticasone) is a nasal steroid. It works directly in your nose to reduce swelling and inflammation caused by allergies.
Type of medication
1st generation
Prescription or OTC
Available as
  • Pill
  • Liquid
  • Nasal spray
Used for (click to learn more)
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
Reviews for Flonase (Fluticasone)
+72% vs. Brotapp (Pseudoephedrine / Brompheniramine)
+43% vs. Brotapp (Pseudoephedrine / Brompheniramine)
-7% vs. Brotapp (Pseudoephedrine / Brompheniramine)
Side effects

We haven’t found good data for Brotapp side effects.

FDA side effect reports for Brotapp »
  • Asthma symptoms 4%
  • Nausea/vomiting 3%
  • Nosebleed 2%
  • Headache 1%
  • Cough 1%
  • Sore throat 1%
More Flonase side effects »
Risk factors for serious side effects
  • Taking with alcohol
  • Taking other medicines that make you drowsy or less alert
  • Women of childbearing age
  • History of high blood pressure
  • Taking MAO inhibitors
  • Age 65 years or older
  • Glaucoma
  • Benign prostatic hypertrophy (BPH)
Detailed Brotapp (Pseudoephedrine / Brompheniramine) risks & warnings »
  • Switching from oral or injectable steroids to inhaled, especially if used long term
  • Using other inhaled steroids with Flonase (Fluticasone)
    • Long-term use
    • Taking more than recommended dose
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Flonase (Fluticasone)
    • Long-term use
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
    • Surgery or trauma to the nose or sinuses
    • Long-term use
    Detailed Flonase (Fluticasone) risks & warnings »
    Pregnancy category
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    • While taking this, avoid alcohol and other drugs that make you drowsy.
    No specific alcohol-related info.
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    No specific sex-related info.No specific sex-related info.
    No specific sleep-related info.No specific sleep-related info.
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    • Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves cold and allergy symptoms. It's good to use if you have congestion, watery eyes, and sneezing.
    • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
    • Brompheniramine (an antihistamine) helps relieve itchy eyes, runny nose, and sneezing.
    • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
    • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
    • Can be used as needed to help control symptoms in people age 13 years or older.
    • Available as a generic medication.
    Downsides and risks
    • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
    • Pseudoephedrine (the decongestant) can make your heart race or make you feel anxious and restless.
    • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
    • The two ingredients in this medication can make you either really tired or keep you wide awake. See how it affects you before doing anything important.
    • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
    • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
    • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
    Tips from our pharmacists for people taking the medication
    • Brompheniramine (the antihistamine ingredient in Brotapp (Pseudoephedrine / Brompheniramine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
    • While taking this, avoid alcohol and other drugs that make you drowsy.
    • Pseudoephedrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
    • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
    • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
    • You need to show an ID to buy Brotapp (Pseudoephedrine / Brompheniramine) in the drugstore because it contains pseudoephedrine.
    • It can take several days for Flonase (Fluticasone) to start working fully.
    • Don't take more of it than was prescribed for you.
    • Blow your nose before using Flonase (Fluticasone).
    • Can cause thrush (a fungal infection) inside the nose and throat.
    • Can also cause a headache, sore throat, or nosebleeds.
    Learn more
    More about BrotappSide effectsReviews & ratingsAlternativesFDA package insert
    More about FlonaseSide effectsReviews & ratingsAlternativesFDA package insert