Compare Brotapp vs. Tylenol Cold and Flu Severe

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Brotapp
(Pseudoephedrine / Brompheniramine)

Tylenol Cold And Flu Severe
(Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin)

Relieves congestion and allergy symptoms. Brotapp (Pseudoephedrine / Brompheniramine) is okay for treating congestion, but it could make you really tired or keep you wide awake.Relieves cold and flu symptoms. Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) is an okay combination medicine that relieves cold and flu symptoms, so make sure you really need all of its ingredients.
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Reviews & ratings
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Side effects
BrotappTylenol Cold and Flu Severe

We haven’t found good data for Brotapp side effects.

FDA side effect reports for Brotapp »

We haven’t found good data for Tylenol Cold and Flu Severe side effects.

FDA side effect reports for Tylenol Cold and Flu Severe »
How it works
BrotappTylenol Cold and Flu Severe
Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves allergy and cold symptoms. Brompheniramine (an antihistamine) treats runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses. Guaifenesin is an expectorant that breaks up and thins out mucus.
Type of medication
BrotappTylenol Cold and Flu Severe
DecongestantAntihistamine
1st generation
Over-the-counter
Pain reliever
APAP
DecongestantCough suppressantExpectorantOver-the-counter
Available as
BrotappTylenol Cold and Flu Severe
  • Pill
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
BrotappTylenol Cold and Flu Severe
Risk factors for serious side effects
BrotappTylenol Cold and Flu Severe
  • Taking with alcohol
  • Taking other medicines that make you drowsy or less alert
  • Women of childbearing age
  • History of high blood pressure
  • Taking MAO inhibitors
  • Age 65 years or older
  • Glaucoma
  • Benign prostatic hypertrophy (BPH)
Detailed Brotapp (Pseudoephedrine / Brompheniramine) risks & warnings »
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
  • History of high blood pressure
  • Taking MAO inhibitors
  • Using other medications that affect serotonin
  • Women of childbearing age
  • History of chronic obstructive pulmonary disease (COPD)
  • History of smoking
Detailed Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) risks & warnings »
Pregnancy category
BrotappTylenol Cold and Flu Severe
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
  • While taking this, avoid alcohol and other drugs that make you drowsy.
No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Brotapp (Pseudoephedrine / Brompheniramine) can make you drowsy and lower your ability to focus, think, and react. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.
No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
BrotappTylenol Cold and Flu Severe
  • Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves cold and allergy symptoms. It's good to use if you have congestion, watery eyes, and sneezing.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
  • Brompheniramine (an antihistamine) helps relieve itchy eyes, runny nose, and sneezing.
  • Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
Downsides and risks
BrotappTylenol Cold and Flu Severe
  • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • Pseudoephedrine (the decongestant) can make your heart race or make you feel anxious and restless.
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • The two ingredients in this medication can make you either really tired or keep you wide awake. See how it affects you before doing anything important.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Two of the medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan stops you from coughing.
Tips from our pharmacists for people taking the medication
BrotappTylenol Cold and Flu Severe
  • Brompheniramine (the antihistamine ingredient in Brotapp (Pseudoephedrine / Brompheniramine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Pseudoephedrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
  • You need to show an ID to buy Brotapp (Pseudoephedrine / Brompheniramine) in the drugstore because it contains pseudoephedrine.
  • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
  • Don't crush, chew, or dissolve the caplets.
  • Follow age-specific dosing instructions on how much to take.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
Learn more
More about BrotappSide effectsReviews & ratingsAlternativesFDA package insert
More about Tylenol Cold and Flu SevereSide effectsReviews & ratingsAlternativesFDA package insert