Compare Brotapp vs. Tylenol Cold And Flu Severe

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves congestion and allergy symptoms.

Brotapp (Pseudoephedrine / Brompheniramine) is okay for treating congestion, but it could make you really tired or keep you wide awake.

Relieves cold and flu symptoms.

Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) is an okay combination medicine that relieves cold and flu symptoms, so make sure you really need all of its ingredients.

Upsides
  • Brotapp (Pseudoephedrine / Brompheniramine) is a combination medicine that relieves cold and allergy symptoms. It's good to use if you have congestion, watery eyes, and sneezing.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
  • Brompheniramine (an antihistamine) helps relieve itchy eyes, runny nose, and sneezing.
  • Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
Downsides
  • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • Pseudoephedrine (the decongestant) can make your heart race or make you feel anxious and restless.
  • Brompheniramine (the antihistamine) can make you dizzy and drowsy. It could increase the risk of falls for elderly people.
  • The two ingredients in this medication can make you either really tired or keep you wide awake. See how it affects you before doing anything important.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Two of the medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan stops you from coughing.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
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Reviews
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Side effects
The Brotapp (Pseudoephedrine / Brompheniramine) FDA package insert doesn’t have numbers about how common side effects are.
The Tylenol Cold And Flu Severe (Acetaminophen / Phenylephrine / Dextromethorphan / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you drowsy or less alert
  • Harm to fetus
    • Women of childbearing age
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Antihistamine side effects
    • Age 65 years or older
    • Glaucoma
    • Benign prostatic hypertrophy (BPH)
See more detailed risks and warnings
  • Liver damage
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other Tylenol-containing medicines
    • History of liver disease
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Harm to fetus
    • Women of childbearing age
  • Chronic cough
    • History of chronic obstructive pulmonary disease (COPD)
    • History of smoking
See more detailed risks and warnings