Compare Buspar vs. Effexor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Buspar (Buspirone)

Prescription only

Effexor (venlafaxine)

Prescription only
Helps you relax.

Buspar (Buspirone) is effective for treating Generalized Anxiety Disorder (GAD), and less effective for short-term use.

4.6/ 7 average rating with 67 reviewsforBuspar
Improves mood and helps you relax.

Effexor (venlafaxine) is good for treating depression and anxiety, but it can cause more withdrawal symptoms if you stop suddenly compared to other antidepressants.

5.1/ 7 average rating with 577 reviewsforEffexor
Upsides
  • Buspar (Buspirone) works very well to control the symptoms of generalized anxiety syndrome (GAD).
  • Buspar (Buspirone) doesn't cause physical dependence or withdrawal symptoms.
  • Buspar (Buspirone) is only available as a generic, so the price can be pretty cheap.
  • Effexor (venlafaxine) effectively treats depression, anxiety, and panic disorder.
  • Effexor (venlafaxine) causes more sleepiness than other antidepressants, so it's beneficial for people who have trouble sleeping.
  • Effexor (venlafaxine) might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood.
  • Effexor (venlafaxine) has several uses, which may be good for people with multiple conditions.
  • Effexor (venlafaxine) is available in generic, which is cheaper.
Downsides
  • Buspar (Buspirone) can take as long as four weeks to become fully effective.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Most people find that it loses effectiveness over long periods of time.
  • Can cause drowsiness or dizziness when you start taking Buspar (Buspirone). Be extremely careful of activities that require mental alertness, such as driving.
  • Effexor (venlafaxine) can cause side effects such as decreased libido and increased blood pressure.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people aged 24 years or younger.
  • Compared to other antidepressants, it's more likely to cause unpleasant withdrawal symptoms if you suddenly stop taking it and can causes more sleepiness.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
Lowest price near you
$4
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$16.2
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Reviews
67 
46%
think this treatment is worth it
45%
think this treatment works well
22%
think this treatment is a hassle

Have you used Buspar (Buspirone)?

Leave a review
577 
62%
think this treatment is worth it
51%
think this treatment works well
23%
think this treatment is a hassle

Have you used Effexor (venlafaxine)?

Leave a review
Side effects
10possible side effects
  • Dizziness
    12%
  • Any side effect
    10%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Central nervous system disturbances
    3%
  • Insomnia
    3%
  • Lightheadedness
    3%
See more detailed side effects
10possible side effects
  • Nausea
    37%
  • Headache
    25%
  • Drowsiness
    23%
  • Dry mouth
    22%
  • Dizziness
    19%
  • Difficulty sleeping
    18%
  • Constipation
    15%
  • Nervousness
    13%
  • Weakness
    12%
  • Sweating
    12%
See more detailed side effects
Risks and warnings
  • Elevated blood pressure

    Taking with MAOIs

    ...and 1 more risk factors

  • Withdrawal reactions

    Taking with or converting from benzodiazepine medicines

  • Abnormal and involuntary muscle movements

    Duration of treatment

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort

  • Withdrawal

    Stopping Effexor (venlafaxine) suddenly

  • Increased bleeding

    Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)

  • Increased blood pressure

  • Bipolar disorder

    History of bipolar disorder

    ...and 1 more risk factors

See more detailed risks and warnings