Compare Buspar vs. Paxil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Buspar (Buspirone)

Prescription only

Paxil (paroxetine)

Prescription only
Helps you relax.

Buspar (Buspirone) is effective for treating Generalized Anxiety Disorder (GAD), and less effective for short-term use.

4.6/ 7 average rating with 67 reviewsforBuspar
Improves mood and anxiety.

Paxil (paroxetine) is effective for treating depression and anxiety, but causes more unwanted side-effects than other medicines that work like it.

4.5/ 7 average rating with 694 reviewsforPaxil
Upsides
  • Buspar (Buspirone) works very well to control the symptoms of generalized anxiety syndrome (GAD).
  • Buspar (Buspirone) doesn't cause physical dependence or withdrawal symptoms.
  • Buspar (Buspirone) is only available as a generic, so the price can be pretty cheap.
  • Available in a cheaper, generic form.
  • Is convenient and can take once a day.
Downsides
  • Buspar (Buspirone) can take as long as four weeks to become fully effective.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Most people find that it loses effectiveness over long periods of time.
  • Can cause drowsiness or dizziness when you start taking Buspar (Buspirone). Be extremely careful of activities that require mental alertness, such as driving.
  • More likely to decrease your sexual appetite and delay or prevent ejaculation than other antidepressants.
  • Like most antidepressants, Paxil (paroxetine) has a high risk of suicidal thoughts and behavior when used in children and adolescents.
  • May not be appropriate for you if you are elderly or suffer from dementia.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release pill
  • Liquid
Price
Lowest price near you
$4
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Lowest price near you
$4
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Reviews
67 
46%
think this treatment is worth it
45%
think this treatment works well
22%
think this treatment is a hassle

Have you used Buspar (Buspirone)?

Leave a review
694 
52%
think this treatment is worth it
39%
think this treatment works well
24%
think this treatment is a hassle

Have you used Paxil (paroxetine)?

Leave a review
Side effects
10possible side effects
  • Dizziness
    12%
  • Any side effect
    10%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Central nervous system disturbances
    3%
  • Insomnia
    3%
  • Lightheadedness
    3%
See more detailed side effects
10possible side effects
  • Abnormal ejaculation
    28%
  • Nausea
    25%
  • Weakness
    22%
  • Drowsiness
    22%
  • Difficulty sleeping
    21%
  • Decreased sexual appetite
    12%
  • Dizziness
    11%
  • Sweating
    9%
  • Dry mouth
    9%
  • Diarrhea
    9%
See more detailed side effects
Risks and warnings
  • Elevated blood pressure

    Taking with MAOIs

    ...and 1 more risk factors

  • Withdrawal reactions

    Taking with or converting from benzodiazepine medicines

  • Abnormal and involuntary muscle movements

    Duration of treatment

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • High levels of serotonin (Serotonin Syndrome)

    Using other medications that affect serotonin levels

  • Withdrawal

    Stopping Paxil (paroxetine) suddenly

  • Increased bleeding risk

    Taking other blood-thinning drugs

See more detailed risks and warnings