Buspar vs. Prozac

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Helps you relax. Buspar (Buspirone) is effective for treating Generalized Anxiety Disorder (GAD), and less effective for short-term use.Improves mood and helps you relax. Prozac (Fluoxetine) is good for treating depression and anxiety. It's more energizing than other antidepressants, but may not be the best choice for people who have trouble sleeping.
How it works
Buspar (Buspirone) is an anti-anxiety medication. It's used to stabilize chemicals in the brain that control mood and nervousness.Prozac (Fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.
Type of medication
Prescription only
Selective serotonin reuptake inhibitor (SSRI)
Prescription only
Available as
  • Pill
  • Pill
  • Delayed release capsule
  • Liquid
Used for (click to learn more)
Find lowest prices
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How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Buspar (Buspirone)

After 4 weeks using Start and Prozac (Fluoxetine), here’s how much better people feel.

Reviews & ratings
Button Group. All currently active
Button Group. All currently active
Reviews for Buspar (Buspirone)
of people say Buspar (Buspirone) is worth it