Compare Buspar vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Buspar
(Buspirone)

Remeron
(mirtazapine)

Helps you relax. Buspar (Buspirone) is effective for treating Generalized Anxiety Disorder (GAD), and less effective for short-term use.Improves mood. Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.63Buspar
Reviews for Buspar
46%
of people (All ages) say Buspar is worth it
45%
say it works well
22%
say it's a big hassle
Have you used Buspar (Buspirone)?
Worth itNot sureNot worth it
Reviews for Remeron
45%
+1% better vs. Buspar
39%
+6% better vs. Buspar
26%
+4% better vs. Buspar
152 reviews
Have you used Remeron (mirtazapine)?
Worth itNot sureNot worth it
Side effects
BusparRemeron
  • Excitement 2%
  • Anger/Hostility 2%
  • Confusion 2%
  • Blurred Vision 2%
  • Diarrhea 2%
  • Numbness 2%
  • Weakness 2%
More Buspar side effects »
  • Back pain 1%
  • Swelling in limbs 1%
  • Muscle pain 1%
  • Tremor 1%
  • Confusion 2%
  • Urinary frequency 1%
  • Abnormal thinking 2%
  • Abnormal dreams 3%
  • Flu syndrome 2%
  • Dizziness 4%
More Remeron side effects »
How it works
BusparRemeron
Buspar (Buspirone) is an anti-anxiety medication. It's used to stabilize chemicals in the brain that control mood and nervousness.Remeron (mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.
Type of medication
BusparRemeron
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
BusparRemeron
  • Pill
  • Pill
  • Dissolving tablet
Used for
BusparRemeron
Risk factors for serious side effects
BusparRemeron
  • Taking with MAOIs
  • Taking with Zyvox or methylene blue
  • Taking with or converting from benzodiazepine medicines
  • Duration of treatment
Detailed Buspar (Buspirone) risks & warnings »
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • History of heart problems
  • History of liver problems
  • Higher dose
Detailed Remeron (mirtazapine) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Interactions
BusparRemeron
No interactions related info.
  • Prescription medications can interact with Remeron (mirtazapine). Let your doctor or pharmacist know if you're on prescription medications currently or within the past 14 days.
Alcohol
BusparRemeron
  • Avoid alcohol when taking Buspar (Buspirone).
No alcohol related info.
Food
BusparRemeron
  • Be consistent in taking Buspar (Buspirone) with or without food.
No food related info.
Sleep
BusparRemeron
  • Can cause drowsiness or dizziness when you start taking Buspar (Buspirone). Be extremely careful of activities that require mental alertness, such as driving.
  • Remeron (mirtazapine) can make you sleepy. It is best to take at bedtime.
  • Can help you fall asleep if you have trouble sleeping.
  • Makes you more tired than other antidepressants.
Weight
BusparRemeron
No weight related info.
  • Remeron (mirtazapine) can raise your appetite and cause you to gain weight. Remeron (mirtazapine) can also raise your cholesterol.
  • Remeron (mirtazapine) can increase your appetite and cause to you to gain weight.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Upsides and benefits
BusparRemeron
  • Buspar (Buspirone) works very well to control the symptoms of generalized anxiety syndrome (GAD).
  • Buspar (Buspirone) doesn't cause physical dependence or withdrawal symptoms.
  • Buspar (Buspirone) is only available as a generic, so the price can be pretty cheap.
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Can help you fall asleep if you have trouble sleeping.
  • Can also help relieve anxiety.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • Available as a generic.
Downsides and risks
BusparRemeron
  • Buspar (Buspirone) can take as long as four weeks to become fully effective.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Most people find that it loses effectiveness over long periods of time.
  • Can cause drowsiness or dizziness when you start taking Buspar (Buspirone). Be extremely careful of activities that require mental alertness, such as driving.
  • Makes you more tired than other antidepressants.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Tips from our pharmacists for people taking the medication
BusparRemeron
  • Take doses at about the same time each day.
  • It can take several weeks to get the full effect.
  • Don't eat or drink grapefruit juice when using Buspar (Buspirone).
  • Don't use Buspar (Buspirone) within two weeks of using an MAO inhibitor (like Eldepryl, Parnate, or Marplan).
  • Be consistent in taking Buspar (Buspirone) with or without food.
  • Avoid alcohol when taking Buspar (Buspirone).
  • Remeron (mirtazapine) can make you sleepy. It is best to take at bedtime.
  • Remeron (mirtazapine) can increase your appetite and cause to you to gain weight.
  • You should not abruptly stop Remeron (mirtazapine) as this could cause serious side effects.
  • Prescription medications can interact with Remeron (mirtazapine). Let your doctor or pharmacist know if you're on prescription medications currently or within the past 14 days.
  • Remeron (mirtazapine) should be protected from light. Keep it in it's original package until ready to use.
  • Remeron (mirtazapine) can cause dry mouth. Try using sugar-free gum or candy to help with dry mouth.
Learn more
More about BusparSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Buspar (Buspirone)?
Worth itNot sureNot worth it
More about RemeronSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Remeron (mirtazapine)?
Worth itNot sureNot worth it