Compare Byetta vs. Metaglip

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Byetta
(exenatide)

Metaglip
(metformin / glipizide)

Lowers your blood sugar. Byetta (Exenatide) helps lower blood sugar for people with diabetes and causes weight loss, but it has to be given by injection and many people have upset stomach.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Byetta (exenatide)
Not enough review data. Review it!
of people (All ages) say Byetta (exenatide) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Byetta (exenatide)?
Worth itNot sureNot worth it
Reviews for Metaglip (metformin / glipizide)
Not enough review data. Review it!
-50% worse vs. Byetta (exenatide)
Not enough review data. Review it!
-50% worse vs. Byetta (exenatide)
Not enough review data. Review it!
Same vs. Byetta (exenatide)
Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it
Side effects
ByettaMetaglip
  • Low blood sugar 6%
  • Nausea 26%
  • Vomiting 14%
  • Diarrhea 10%
  • Headache 10%
  • Constipation 8%
  • Dizziness 3%
More Byetta side effects »

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
How it works
ByettaMetaglip
Byetta (Exenatide) is a medication for diabetes. It stimulates your body to produce and release more insulin, lower the sugar hormone (glucagon), and slow down digestion.Coming soon.
Type of medication
ByettaMetaglip
Prescription only
Available as
ByettaMetaglip
  • Injection
  • Pill
Used for
ByettaMetaglip
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
ByettaMetaglip
  • Severe renal impairment
  • End-stage renal disease
  • Severe gastrointestinal disease
  • Gastroparesis
Detailed Byetta (exenatide) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    ByettaMetaglip
    • Because Byetta (Exenatide) can interact with antibiotics and birth control pills, you can't take it until one hour after these medications.
    No interactions related info.
    Food
    ByettaMetaglip
    • Eat regular, balanced meals to avoid low blood sugar.
    No food related info.
    Kidneys and liver
    ByettaMetaglip
    • If you have severe kidney or liver problems, you should not take Byetta (Exenatide). Talk to your doctor about testing your kidneys before starting Byetta (Exenatide). People taking medications that are damaging to kidneys such as ACE inhibitors, NSAIDs or diuretics in addition to Byetta (Exenatide) may notice nausea, vomiting, or diarrhea.
    No kidneys and liver related info.
    Pain
    ByettaMetaglip
    • Using Byetta (Exenatide) has been associated with stomach pain, nausea, vomiting and diarrhea. If you have severe gastrointestinal disease such as Crohn’s Disease or Ulcerative Colitis, you should talk to your doctor about using a different medication for diabetes. You should not use Byetta (Exenatide) if you have gastroparesis, a condition that causes slow or irregular digestion. Gastroparesis can be common for people that have had uncontrolled diabetes for a while.
    No pain related info.
    Upsides and benefits
    ByettaMetaglip
    • Lowers A1c levels by 1% (A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs.
    • Has a lower chance of causing low blood sugar than medications like glyburide or insulin.
    • Can lower your appetite by making you feel full. Some people also lose weight when taking Byetta (Exenatide).
    • Byetta (Exenatide) is not a replacement for diabetes pills, but you may be able to use it alone without the need for pills.
    • The injectable “pen” has easy to use doses which you may find more convenient than other types of injections.
    Coming soon
    Downsides and risks
    ByettaMetaglip
    • Only lowers A1c levels by 1%, which may not be enough to get your blood sugar in the safe range.
    • Byetta (Exenatide) must be injected twice a day.
    • Up to 40% of people taking Byetta (Exenatide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
    • Because Byetta (Exenatide) can interact with antibiotics and birth control pills, you can't take it until one hour after these medications.
    • Other diabetes medications work as well and are cheaper.
    Coming soon
    Tips from our pharmacists for people taking the medication
    ByettaMetaglip
    • Store in the refrigerator until opening. Do not freeze.
    • Give injections in your belly, thighs, or upper arm within an hour of your two main meals of the day (separate doses by 6 or more hours).
    • Change the needle and prime the pen every time you inject.
    • It’s not safe to share this medication with other people, even if you change the needle.
    • Don’t mix with insulin; give separate injections. Can be given at the same time as insulin, but in different injection areas.
    • Eat regular, balanced meals to avoid low blood sugar.
    • It's best to check your blood sugar at least once a day using a home blood sugar monitor to make sure your medication is working and is safe. Some people may need to test more often, ask your doctor.
    Coming soon
    Learn more
    More about ByettaSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Byetta (exenatide)?
    Worth itNot sureNot worth it
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it