Compare Bystolic vs. Norvasc

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Bystolic
(Nebivolol)

Norvasc
(Amlodipine)

Lowers blood pressure and controls heart rate. Bystolic (Nebivolol) is a good blood pressure-lowering medicine for people with heart conditions, and has fewer side effects than other beta blockers, but it's expensive. You can't miss doses.Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.76056338028169Bystolic
Reviews for Bystolic (Nebivolol)
51%
of people say Bystolic (Nebivolol) is worth it
46%
say it works well
18%
say it's a big hassle
Reviews for Norvasc (Amlodipine)
59%
+8% vs. Bystolic (Nebivolol)
50%
+4% vs. Bystolic (Nebivolol)
14%
+4% vs. Bystolic (Nebivolol)
Side effects
BystolicNorvasc
  • Fatigue 4%
  • Headache 3%
  • Dizziness 2%
  • Diarrhea 1%
More Bystolic side effects »
  • Swelling due to excess fluid 10%
  • Fatigue 2%
  • Nausea 1%
  • Dizziness 1%
More Norvasc side effects »
How it works
BystolicNorvasc
Bystolic (Nebivolol) is a selective beta blocker that works specifically on the heart. It lowers blood pressure by slowing down the heart and making it work less to pump.Norvasc (Amlodipine) is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.
Type of medication
BystolicNorvasc
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Calcium channel blocker
Prescription only
Available as
BystolicNorvasc
  • Pill
  • Pill
Used for (click to learn more)
BystolicNorvasc
Risk factors for serious side effects
BystolicNorvasc
  • Sudden discontinuation of medicine
  • History of asthma
  • History of diabetes
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Bystolic (Nebivolol) risks & warnings »
  • Age 65 years or older
  • History of heart problems
  • Liver disease
  • History of blood vessel disease
  • History of heart failure
  • History of kidney disease
  • Obesity
Detailed Norvasc (Amlodipine) risks & warnings »
Pregnancy category
BystolicNorvasc
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.
  • Norvasc (Amlodipine) can cause varying degrees of swelling in your limbs. The most commonly affected areas are your feet, ankles, legs, or occasionally your arms. Swelling may be worse if you have other conditions that makes it hard for your body to get rid of fluids such as congestive heart failure or kidney disease. If your swelling is caused by Norvasc (Amlodipine), it should improve when you stop taking the medication. If the swelling is bothersome, a different medication may be better for you.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
BystolicNorvasc
  • Controls your heart rate to reduce work for your heart.
  • A first-line treatment for heart failure and heart attack.
  • Helps to lower blood pressure if you can't use first-choice treatments or need additional blood pressure control.
  • Many beta blockers can worsen asthma or cause headaches, but Bystolic usually doesn't because it targets the heart more specifically and causes fewer side effects.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
Downsides and risks
BystolicNorvasc
  • Not available in less expensive generic form.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Bystolic suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
Tips from our pharmacists for people taking the medication
BystolicNorvasc
  • Can cause headache, dizziness, or feeling short of breath in the first few days.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Don't stop taking this medicine suddenly.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause dizziness in the first few days.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
Learn more
More about BystolicSide effectsReviews & ratingsAlternativesFDA package insert
More about NorvascSide effectsReviews & ratingsAlternativesFDA package insert