Compare Cafergot vs. Maxalt

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cafergot (ergotamine / caffeine)

Prescription only

Maxalt (Rizatriptan)

Prescription only
Treats migraine headaches.

Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.

Treats migraine headaches.

Maxalt (Rizatriptan) is great for relieving short migraines, but doesn't work as well for long-lasting headaches.

5.3/ 7 average rating with 26 reviewsforMaxalt
Upsides
  • Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
  • Triptans like Maxalt (Rizatriptan) are considered the first-choice treatment to relieve moderate to severe migraine-type headaches.
  • It can also be used to treat tension-type headaches.
  • Not all triptans work the same way for people, so you can try multiple ones to find the right medication for you.
  • You don't need to drink water with the orally disintegrating tablet for it to work, so this could be a good medication for people who can't keep water down when they have a migraine.
Downsides
  • Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
  • Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
  • Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
  • Maxalt (Rizatriptan) doesn’t prevent migraines or tension headaches, but only works once the headache starts.
  • It can cause rebound headaches if it’s used too often.
  • You need to wait at least 2 hours after your first dose to take a second dose.
  • May not be the best choice if you have long, drawn-out headaches. Ask your doctor about other triptans that can last longer than Maxalt (Rizatriptan).
  • Not a good choice if you have heart disease or if you’re pregnant or breast-feeding.
Used for
Dosage forms
  • Pill
  • Suppository
  • Pill
  • Dissolving tablet
Price
Lowest price near you
$653.26
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Lowest price near you
$17.04
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Reviews
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26 
81%
think this treatment is worth it
62%
think this treatment works well
19%
think this treatment is a hassle

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Side effects
The Cafergot (ergotamine / caffeine) FDA package insert doesn’t have numbers about how common side effects are.
The Maxalt (Rizatriptan) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart and circulation problems

    Overdosing Cafergot (ergotamine / caffeine)

    ...and 1 more risk factors

  • Dependency and withdrawal

    Taking Cafergot (ergotamine / caffeine) regularly for months

See more detailed risks and warnings
  • Tightening of blood vessels (myocardial angina, ischemia, or infarction)

    History of heart problems

    ...and 5 more risk factors

  • Stroke

    History of heart problems

    ...and 5 more risk factors

  • Serotonin syndrome

    Patients taking SSRIs and SNRIs

  • High blood pressure

    History of high blood pressure

  • Seizures

    History of seizures

  • Phenylketonuria (PKU)

    Phenylketonuria (PKU)

See more detailed risks and warnings