Compare Cafergot vs. Tenex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cafergot (ergotamine / caffeine)

Prescription only

Tenex (Guanfacine)

Prescription only
Treats migraine headaches.

Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.

Treats ADHD and lowers blood pressure.

Tenex (Guanfacine) can be used to treat both blood pressure and ADHD, but it's not recommended as a first-line treatment for either problem.

Upsides
  • Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
  • The same medication treats two different things, high blood pressure and attention deficit hyperactivity disorder (ADHD).
  • It's not a "controlled medication".
  • Used to control ADHD when stimulant medications haven't worked or can't be used due to other medical problems.
  • Available as a generic medication, so it should be more affordable than other options.
Downsides
  • Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
  • Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
  • Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
  • Doesn't control ADHD as well as stimulants do, so it's used as a second-line medication.
  • Not a preferred drug to control blood pressure.
  • Can't be stopped suddenly, especially for blood pressure, since the blood pressure can dramatically increase.
Used for
Dosage forms
  • Pill
  • Suppository
  • Pill
  • Extended release
Price
Lowest price near you
$653.26
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Lowest price near you
$4
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Reviews
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Side effects
The Cafergot (ergotamine / caffeine) FDA package insert doesn’t have numbers about how common side effects are.
7possible side effects
  • Dry Mouth
    10%
  • Somnolence
    10%
  • Headache
    7%
  • Fatigue
    5%
  • Any side effect
    5%
  • Asthenia
    3%
  • Dizziness
    2%
See more detailed side effects
Risks and warnings
  • Heart and circulation problems

    Overdosing Cafergot (ergotamine / caffeine)

    ...and 1 more risk factors

  • Dependency and withdrawal

    Taking Cafergot (ergotamine / caffeine) regularly for months

See more detailed risks and warnings
  • Sedation

    Taking other medications that cause sedation or sleepiness

  • Rebound high blood pressure

    Stopping Tenex (Guanfacine) suddenly to treat high blood pressure

See more detailed risks and warnings