Compare Cafergot vs. Tenex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cafergot
(Ergotamine / Caffeine)

Tenex
(Guanfacine)

Coming soon.Treats ADHD and lowers blood pressure. Tenex (Guanfacine) can be used to treat both blood pressure and ADHD, but it's not recommended as a first-line treatment for either problem.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Cafergot (Ergotamine / Caffeine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Tenex (Guanfacine)?
Worth itNot sureNot worth it
Side effects
CafergotTenex

We haven’t found good data for Cafergot side effects.

FDA side effect reports for Cafergot »
  • Drowsiness 31%
  • Fatigue 8%
  • Dizziness 7%
  • Headache 5%
More Tenex side effects »
How it works
CafergotTenex
Coming soon.Tenex (Guanfacine) is a centrally-acting alpha agonist medication. It lowers blood pressure by slowing down the heart rate and relaxing the blood vessels. It's not clear how Tenex (Guanfacine) works in ADHD, but it's used when stimulants haven't worked or can't be used in people.
Type of medication
CafergotTenex
Coming soon.
Antihypertensive
Alpha agonist
Prescription only
Available as
CafergotTenex
  • Pill
  • Suppository
  • Pill
  • Extended release
Used for (click to learn more)
CafergotTenex
  • Migraine Vascular headache
Risk factors for serious side effects
CafergotTenex
Coming soon.
  • Taking other medications that cause sedation or sleepiness
  • Stopping Tenex (Guanfacine) suddenly to treat high blood pressure
Detailed Tenex (Guanfacine) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Alcohol
CafergotTenex
No alcohol related info.
  • Limit the amount of alcohol you drink while taking this.
Sleep
CafergotTenex
No sleep related info.
  • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
  • People report having sleepiness or sedation while on Tenex (Guanfacine). You're at higher risk for this if you're taking other medications that have similar effects. Don't drive or do anything that requires concentration until you know how Tenex (Guanfacine) affects you.
Upsides and benefits
CafergotTenex
Coming soon
  • The same medication treats two different things, high blood pressure and attention deficit hyperactivity disorder (ADHD).
  • It's not a "controlled medication".
  • Used to control ADHD when stimulant medications haven't worked or can't be used due to other medical problems.
  • Available as a generic medication, so it should be more affordable than other options.
Downsides and risks
CafergotTenex
Coming soon
  • Doesn't control ADHD as well as stimulants do, so it's used as a second-line medication.
  • Not a preferred drug to control blood pressure.
  • Can't be stopped suddenly, especially for blood pressure, since the blood pressure can dramatically increase.
Tips from our pharmacists for people taking the medication
CafergotTenex
Coming soon
  • Don't stop taking Tenex (Guanfacine) without talking to your doctor first.
  • Limit the amount of alcohol you drink while taking this.
  • Drink plenty of liquids and don't get overheated while taking Tenex (Guanfacine).
  • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
  • Can take up to 2 weeks for the maximum effect.
Learn more
More about CafergotSide effectsFDA package insert
Have you used Cafergot (Ergotamine / Caffeine)?
Worth itNot sureNot worth it
More about TenexSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tenex (Guanfacine)?
Worth itNot sureNot worth it