Compare Cafergot vs. Tenex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cafergot
(Ergotamine / Caffeine)

Tenex
(Guanfacine)

Coming soon.Treats ADHD and lowers blood pressure. Tenex (Guanfacine) can be used to treat both blood pressure and ADHD, but it's not recommended as a first-line treatment for either problem.
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Reviews & ratings
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Side effects
CafergotTenex

We haven’t found good data for Cafergot side effects.

FDA side effect reports for Cafergot »
  • Drowsiness 31%
  • Fatigue 8%
  • Dizziness 7%
  • Headache 5%
More Tenex side effects »
How it works
CafergotTenex
Coming soon.Tenex (Guanfacine) is a centrally-acting alpha agonist medication. It lowers blood pressure by slowing down the heart rate and relaxing the blood vessels. It's not clear how Tenex (Guanfacine) works in ADHD, but it's used when stimulants haven't worked or can't be used in people.
Type of medication
CafergotTenex
Coming soon.
Antihypertensive
Alpha agonist
Prescription only
Available as
CafergotTenex
  • Pill
  • Suppository
  • Pill
  • Extended release
Used for (click to learn more)
CafergotTenex
  • Migraine Vascular headache
Risk factors for serious side effects
CafergotTenex
Coming soon.
  • Taking other medications that cause sedation or sleepiness
  • Stopping Tenex (Guanfacine) suddenly to treat high blood pressure
Detailed Tenex (Guanfacine) risks & warnings »
Pregnancy category
CafergotTenex
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
Alcohol
No specific alcohol-related info.
  • Limit the amount of alcohol you drink while taking this.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
CafergotTenex
Coming soon.
  • The same medication treats two different things, high blood pressure and attention deficit hyperactivity disorder (ADHD).
  • It's not a "controlled medication".
  • Used to control ADHD when stimulant medications haven't worked or can't be used due to other medical problems.
  • Available as a generic medication, so it should be more affordable than other options.
Downsides and risks
CafergotTenex
Coming soon.
  • Doesn't control ADHD as well as stimulants do, so it's used as a second-line medication.
  • Not a preferred drug to control blood pressure.
  • Can't be stopped suddenly, especially for blood pressure, since the blood pressure can dramatically increase.
Tips from our pharmacists for people taking the medication
CafergotTenex
Coming soon.
  • Don't stop taking Tenex (Guanfacine) without talking to your doctor first.
  • Limit the amount of alcohol you drink while taking this.
  • Drink plenty of liquids and don't get overheated while taking Tenex (Guanfacine).
  • You can feel sleepy the first few times you take it, or when your dose is increased. Don't drive or do anything that requires concentration until you know how the medication affects your body.
  • Can take up to 2 weeks for the maximum effect.
Learn more
More about CafergotSide effectsFDA package insert
More about TenexSide effectsReviews & ratingsAlternativesFDA package insert