Compare Calan vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Calan
(verapamil)

Coreg
(carvedilol)

Lowers blood pressure and controls heart rate. Verapamil works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Calan
Reviews for Calan
35%
of people (All ages) say Calan is worth it
33%
say it works well
21%
say it's a big hassle
Have you used Calan (verapamil)?
Worth itNot sureNot worth it
Reviews for Coreg
53%
-18% worse vs. Calan
46%
-13% worse vs. Calan
18%
-3% worse vs. Calan
406 reviews
Have you used Coreg (carvedilol)?
Worth itNot sureNot worth it
Side effects
CalanCoreg
  • Constipation 7%
  • Dizziness 3%
  • Nausea 3%
  • Hypotension 3%
  • Headache 2%
  • Edema 2%
  • CHF and pulmonary edema 2%
  • Fatigue 2%
  • Lethargy 3%
  • Dyspepsia 3%
More Calan side effects »
  • Dizziness 13%
  • Fatigue 2%
  • Hyperglycemia 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Bradycardia 8%
  • Hypotension 6%
  • Headache 1%
More Coreg side effects »
How it works
CalanCoreg
Verapamil is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
CalanCoreg
Prescription onlyPrescription only
Available as
CalanCoreg
  • Pill
  • Extended release
  • Delayed release capsule
  • Pill
  • Extended release
Used for
CalanCoreg
Risk factors for serious side effects
CalanCoreg
  • Severe left ventricular dysfunction (ejection fraction <30%)
  • Taking beta-blockers
  • History of liver disease
  • History of kidney disease
Detailed Calan (verapamil) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed Coreg (carvedilol) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
CalanCoreg
  • Interacts with grapefruit and the cholesterol medicine Simvastatin.
No interactions related info.
Alcohol
CalanCoreg
  • Don't drink too much alcohol while taking this medicine.
  • Not a good medication for you if you drink alcohol.
No alcohol related info.
Food
CalanCoreg
No food related info.
  • Take it with food.
  • You have to take Carvedilol with food.
Kidneys and liver
CalanCoreg
  • Your doctor may check your liver regularly, as there have been reports of liver damage which can only be seen through blood tests. If you do have a history of liver disease, let your doctor know.
  • Your doctor may monitor your heart to see if changes to its electrical system may occur, especially if you have had liver or kidney disease in the past.
No kidneys and liver related info.
Upsides and benefits
CalanCoreg
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
Downsides and risks
CalanCoreg
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Verapamil than men.
  • You can't miss doses. Stopping Verapamil suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you drink alcohol.
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
CalanCoreg
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with grapefruit and the cholesterol medicine Simvastatin.
  • Can cause constipation and headache.
  • Don't drink too much alcohol while taking this medicine.
  • Your doctor might do routine blood tests to check your liver function.
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
Learn more
More about CalanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Calan (verapamil)?
Worth itNot sureNot worth it
More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coreg (carvedilol)?
Worth itNot sureNot worth it