Compare Calan vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Calan
(Verapamil)

Lopressor
(Metoprolol Tartrate)

Lowers blood pressure and controls heart rate. Verapamil works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Calan
Reviews for Calan (Verapamil)
35%
of people (All ages) say Calan (Verapamil) is worth it
33%
say it works well
21%
say it's a big hassle
Have you used Calan (Verapamil)?
Worth itNot sureNot worth it
Reviews for Lopressor (Metoprolol Tartrate)
62%
+27% better vs. Calan (Verapamil)
47%
+14% better vs. Calan (Verapamil)
15%
+6% better vs. Calan (Verapamil)
464 reviews
Have you used Lopressor (Metoprolol Tartrate)?
Worth itNot sureNot worth it
Side effects
CalanLopressor
  • Constipation 7%
  • Dizziness 3%
  • Nausea 3%
  • Low blood pressure 3%
  • Headache 2%
  • Swelling due to excess fluid 2%
  • Chf and pulmonary edema 2%
  • Fatigue 2%
  • Lack of energy 3%
  • Indigestion 3%
More Calan side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching 5%
  • Shortness of breath 3%
  • Abnormally slow heartbeat 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
CalanLopressor
Verapamil is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
CalanLopressor
Prescription only
Prescription only
Available as
CalanLopressor
  • Pill
  • Extended release
  • Delayed release capsule
  • Pill
Used for
CalanLopressor
Risk factors for serious side effects
CalanLopressor
  • Severe left ventricular dysfunction (ejection fraction <30%)
  • Taking beta-blockers
    • History of liver disease
    • History of kidney disease
    • History of liver disease
    Detailed Calan (Verapamil) risks & warnings »
    • Diabetes
      • Coronary artery disease
      • Heart failure
      • Major surgery requiring anesthesia
      • History of asthma
      Detailed Lopressor (Metoprolol Tartrate) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Interactions
      CalanLopressor
      • Interacts with grapefruit and the cholesterol medicine Simvastatin.
      No interactions related info.
      Alcohol
      CalanLopressor
      • Not a good medication for you if you drink alcohol.
      • Don't drink too much alcohol while taking this medicine.
      No alcohol related info.
      Food
      CalanLopressor
      No food related info.
      • Take it with food.
      Kidneys and liver
      CalanLopressor
      • Your doctor may check your liver regularly, as there have been reports of liver damage which can only be seen through blood tests. If you do have a history of liver disease, let your doctor know.
      • Your doctor may monitor your heart to see if changes to its electrical system may occur, especially if you have had liver or kidney disease in the past.
      No kidneys and liver related info.
      Upsides and benefits
      CalanLopressor
      • A first-choice blood pressure treatment for many people.
      • Calcium channel blockers work especially well for African Americans to lower blood pressure.
      • You can take it alone or with other medicines to help lower blood pressure.
      • Lowers the risk of heart attack and stroke.
      • Prevents heart-related chest pain (angina) if you take it regularly.
      • Treats certain abnormal heart rhythms.
      • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
      • A first-choice treatment for heart failure. May prevent long-term heart damage.
      • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
      Downsides and risks
      CalanLopressor
      • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
      • Women are more likely to have side effects (especially swelling) from Verapamil than men.
      • You can't miss doses. Stopping Verapamil suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
      • Not a good medication for you if you drink alcohol.
      • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
      • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
      • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
      • Can hide symptoms of low blood sugar if you're diabetic.
      • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
      Tips from our pharmacists for people taking the medication
      CalanLopressor
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Interacts with grapefruit and the cholesterol medicine Simvastatin.
      • Can cause constipation and headache.
      • Don't drink too much alcohol while taking this medicine.
      • Your doctor might do routine blood tests to check your liver function.
      • Take it with food.
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Can cause fatigue and headache.
      • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
      • Don't stop taking this medicine suddenly.
      • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
      Learn more
      More about CalanSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Calan (Verapamil)?
      Worth itNot sureNot worth it
      More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Lopressor (Metoprolol Tartrate)?
      Worth itNot sureNot worth it