Compare Calan vs. felodipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Calan
(verapamil)

Plendil
(felodipine)

Lowers blood pressure and controls heart rate. Verapamil works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure. Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Calan
Reviews for Calan (verapamil)
35%
of people (All ages) say Calan (verapamil) is worth it
33%
say it works well
21%
say it's a big hassle
Have you used Calan (verapamil)?
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Have you used Plendil (felodipine)?
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Side effects
Calanfelodipine
  • Constipation 7%
  • Dizziness 3%
  • Nausea 3%
  • Low blood pressure 3%
  • Headache 2%
  • Swelling due to excess fluid 2%
  • Chf and pulmonary edema 2%
  • Fatigue 2%
  • Lack of energy 3%
  • Indigestion 3%
More Calan side effects »
  • Headache 1%
  • Flushing 3%
  • Upset stomach 3%
  • Weakness 1%
  • Colds or flu 2%
  • Runny nose 2%
  • Sneezing 2%
  • Rash 1%
More felodipine side effects »
How it works
Calanfelodipine
Verapamil is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Plendil (felodipine) is a calcium channel blocker. It lowers blood pressure by relaxing heart tissue and lowering pressure in blood vessels, which causes your blood pressure to go down.
Type of medication
Calanfelodipine
Prescription only
Prescription only
Available as
Calanfelodipine
  • Pill
  • Extended release
  • Delayed release capsule
  • Extended release
Used for
Calanfelodipine
Risk factors for serious side effects
Calanfelodipine
  • Severe left ventricular dysfunction (ejection fraction <30%)
  • Taking beta-blockers
    • History of liver disease
    • History of kidney disease
    • History of liver disease
    Detailed Calan (verapamil) risks & warnings »
    • Over age 65
    • Taking in combination with a beta-blocker
    • Liver disease
    • Over age 65
    • History of heart failure
    • History of kidney disease
    Detailed Plendil (felodipine) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    Calanfelodipine
    • Interacts with grapefruit and the cholesterol medicine Simvastatin.
    No interactions related info.
    Alcohol
    Calanfelodipine
    • Not a good medication for you if you drink alcohol.
    • Don't drink too much alcohol while taking this medicine.
    No alcohol related info.
    Food
    Calanfelodipine
    No food related info.
    • Plendil (felodipine) can be taken without food or with a light low fat meal.
    Kidneys and liver
    Calanfelodipine
    • Your doctor may check your liver regularly, as there have been reports of liver damage which can only be seen through blood tests. If you do have a history of liver disease, let your doctor know.
    • Your doctor may monitor your heart to see if changes to its electrical system may occur, especially if you have had liver or kidney disease in the past.
    No kidneys and liver related info.
    Upsides and benefits
    Calanfelodipine
    • A first-choice blood pressure treatment for many people.
    • Calcium channel blockers work especially well for African Americans to lower blood pressure.
    • You can take it alone or with other medicines to help lower blood pressure.
    • Lowers the risk of heart attack and stroke.
    • Prevents heart-related chest pain (angina) if you take it regularly.
    • Treats certain abnormal heart rhythms.
    • Plendil (felodipine) is a good option for people with high blood pressure.
    • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
    Downsides and risks
    Calanfelodipine
    • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
    • Women are more likely to have side effects (especially swelling) from Verapamil than men.
    • You can't miss doses. Stopping Verapamil suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Not a good medication for you if you drink alcohol.
    • Plendil (felodipine) may not work as well as other calcium channel blockers.
    • It can lead to more swelling in your arms and legs when taken at higher doses.
    • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
    • Plendil (felodipine) can't be crushed or cut into two.
    Tips from our pharmacists for people taking the medication
    Calanfelodipine
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Interacts with grapefruit and the cholesterol medicine Simvastatin.
    • Can cause constipation and headache.
    • Don't drink too much alcohol while taking this medicine.
    • Your doctor might do routine blood tests to check your liver function.
    • Can cause swelling in your legs or ankles.
    • Can also cause swelling in your gums.
    • Plendil (felodipine) can be taken without food or with a light low fat meal.
    • Avoid grapefruit and grapefruit juice while taking Plendil (felodipine).
    • You might feel lightheaded or dizzy when first starting Plendil (felodipine).
    Learn more
    More about CalanSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Calan (verapamil)?
    Worth itNot sureNot worth it
    More about felodipineSide effectsAlternativesFDA package insert
    Have you used Plendil (felodipine)?
    Worth itNot sureNot worth it