Compare Calan vs. Prazosin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Calan
(verapamil)

Minipress
(prazosin)

Lowers blood pressure and controls heart rate. Verapamil works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and makes it easier to urinate. Prazosin is used mostly to make urination easier for men with an enlarged prostate, but it can cause dizziness.
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Coupons for Calan
Best available price for 60 (120mg) tablets of verapamil
Coupons for Prazosin
Best available price for 30 (1mg) capsules of prazosin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Calan
Reviews for Calan
35%
of people (All ages) say Calan is worth it
33%
say it works well
21%
say it's a big hassle
Have you used Calan (verapamil)?
Worth itNot sureNot worth it
Reviews for Prazosin
46%
-11% worse vs. Calan
29%
+4% better vs. Calan
15%
-6% worse vs. Calan
Have you used Minipress (prazosin)?
Worth itNot sureNot worth it
Side effects
CalanPrazosin
  • Constipation 7%
  • Dizziness 3%
  • Nausea 3%
  • Low blood pressure 3%
  • Headache 2%
  • Swelling due to excess fluid 2%
  • Chf and pulmonary edema 2%
  • Fatigue 2%
  • Lack of energy 3%
  • Indigestion 3%
More Calan side effects »
  • Dizziness 10%
  • Headache 8%
  • Drowsiness 8%
  • Lack of energy 7%
  • Weakness 7%
  • Heart pounding or racing sensation 5%
  • Nausea 5%
More Prazosin side effects »
How it works
CalanPrazosin
Verapamil is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Prazosin is a selective alpha blocker. It lowers blood pressure by relaxing blood vessels. It also relaxes the urethra and prostate, which makes it easier to urinate.
Type of medication
CalanPrazosin
Prescription onlyPrescription only
Available as
CalanPrazosin
  • Pill
  • Extended release
  • Delayed release capsule
  • Pill
Used for
CalanPrazosin
Risk factors for serious side effects
CalanPrazosin
  • Severe left ventricular dysfunction (ejection fraction <30%)
  • Taking beta-blockers
  • History of liver disease
  • History of kidney disease
Detailed Calan (verapamil) risks & warnings »
  • Age 65 years or older
Detailed Minipress (prazosin) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
CalanPrazosin
  • Interacts with grapefruit and the cholesterol medicine Simvastatin.
No interactions related info.
Alcohol
CalanPrazosin
  • Don't drink too much alcohol while taking this medicine.
  • Not a good medication for you if you drink alcohol.
No alcohol related info.
Food
CalanPrazosin
No food related info.
  • Take with food or at bedtime to avoid side effects.
Kidneys and liver
CalanPrazosin
  • Your doctor may check your liver regularly, as there have been reports of liver damage which can only be seen through blood tests. If you do have a history of liver disease, let your doctor know.
  • Your doctor may monitor your heart to see if changes to its electrical system may occur, especially if you have had liver or kidney disease in the past.
No kidneys and liver related info.
Sleep
CalanPrazosin
No sleep related info.
  • Can cause drowsiness, headache, dizziness, and nausea.
Upsides and benefits
CalanPrazosin
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Makes urination easier in men with an enlarged prostate.
  • Helps people with PTSD get better sleep with fewer, less-intense nightmares.
Downsides and risks
CalanPrazosin
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Verapamil than men.
  • You can't miss doses. Stopping Verapamil suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you drink alcohol.
  • Not the best medicine to lower blood pressure by itself.
  • Likely to cause orthostatic hypotension. This means dizziness when you change positions (like standing up) because your blood pressure doesn't adjust quickly enough.
  • Not preferred for people 65 years or older.
Tips from our pharmacists for people taking the medication
CalanPrazosin
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with grapefruit and the cholesterol medicine Simvastatin.
  • Can cause constipation and headache.
  • Don't drink too much alcohol while taking this medicine.
  • Your doctor might do routine blood tests to check your liver function.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause drowsiness, headache, dizziness, and nausea.
  • Take with food or at bedtime to avoid side effects.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Recheck your blood pressure 1 week after starting this medicine.
Learn more
More about CalanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Calan (verapamil)?
Worth itNot sureNot worth it
More about PrazosinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Minipress (prazosin)?
Worth itNot sureNot worth it