Compare Captopril vs. Altace

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Capoten
(captopril)

Altace
(ramipril)

Lowers blood pressure. Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.Lowers blood pressure. Altace (ramipril) is a good blood pressure-lowering medicine that protects your kidney function. It's also a good option if you have trouble swallowing pills since you can open the capsules.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Captopril
Reviews for Captopril
34%
of people (All ages) say Captopril is worth it
25%
say it works well
25%
say it's a big hassle
106 reviews
Have you used Capoten (captopril)?
Worth itNot sureNot worth it

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Have you used Altace (ramipril)?
Worth itNot sureNot worth it
Side effects
CaptoprilAltace
  • Rash 7%
  • Flushing 5%
  • Abnormal sense of taste 4%
  • Itching 2%
  • Cough 2%
More Captopril side effects »
  • Low blood pressure 6%
  • Increased cough 4%
  • Dizziness 1%
  • Chest pain 1%
  • Nausea 1%
  • Low blood pressure when standing up 1%
  • Fainting 1%
  • Vomiting 1%
  • Vertigo 1%
More Altace side effects »
How it works
CaptoprilAltace
Captopril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Altace (ramipril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that usually tightens blood vessels. By making blood vessels relax, it lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
CaptoprilAltace
Prescription onlyPrescription only
Available as
CaptoprilAltace
  • Pill
  • Pill
Used for
CaptoprilAltace
Risk factors for serious side effects
CaptoprilAltace
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Capoten (captopril) risks & warnings »
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Using salt substitutes
Detailed Altace (ramipril) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
CaptoprilAltace
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check how your kidneys are working.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Upsides and benefits
CaptoprilAltace
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Altace (ramipril) is a first-choice blood pressure treatment for many people.
  • It lowers your risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Altace (ramipril) is the only ACE inhibitor that you can open and sprinkle in applesauce or water.
Downsides and risks
CaptoprilAltace
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Some people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • You'll need to get routine blood tests to see how this medicine is affecting your body.
  • Women, be sure to use contraception while taking this medication since it can harm a fetus. It's also not safe to use if you're already pregnant.
Tips from our pharmacists for people taking the medication
CaptoprilAltace
  • Take 1 hour before or 2 hours after eating.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Altace (ramipril) can make you feel dizzy for the first few days.
  • Check your blood pressure one week after starting Altace (ramipril) or changing your dose.
  • Tell your doctor about any dizziness, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check how your kidneys are working.
  • Don't take Altace (ramipril) if you're pregnant.
  • If you can't swallow the capsule, you can open it up and mix with water, apple juice, or apple sauce.
Learn more
More about CaptoprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Capoten (captopril)?
Worth itNot sureNot worth it
More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Altace (ramipril)?
Worth itNot sureNot worth it