Compare Captopril vs. Altace

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Capoten
(Captopril)

Altace
(Ramipril)

Lowers blood pressure. Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.Lowers blood pressure. Altace (Ramipril) is a good blood pressure-lowering medicine that protects kidney function. Easy to use if you can't swallow whole capsules.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Captopril
Reviews for Capoten (Captopril)
34%
of people (All ages) say Capoten (Captopril) is worth it
25%
say it works well
25%
say it's a big hassle
106 reviews
Have you used Capoten (Captopril)?
Worth itNot sureNot worth it

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Have you used Altace (Ramipril)?
Worth itNot sureNot worth it
Side effects
CaptoprilAltace

The Captopril FDA package insert doesn’t have numbers about how common side effects are.

More about Captopril side effects »

The Altace FDA package insert doesn’t have numbers about how common side effects are.

More about Altace side effects »
How it works
CaptoprilAltace
Captopril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Altace (Ramipril) is an angiotensin converting enzyme (ACE) inhibitor. By blocking a chemical that usually tightens blood vessels, it makes blood vessels relax. This lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
CaptoprilAltace
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Available as
CaptoprilAltace
  • Pill
  • Pill
Used for (click to learn more)
CaptoprilAltace
Risk factors for serious side effects
CaptoprilAltace
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed risks & warnings »
  • Women of childbearing age
  • History of ACE inhibitor induced cough
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
Detailed risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
CaptoprilAltace
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check how your kidneys are working.
Upsides and benefits
CaptoprilAltace
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • The only ACE inhibitor that comes in a capsule that you can sprinkle in applesauce or water.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides and risks
CaptoprilAltace
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Up to 1 and 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
CaptoprilAltace
  • Take 1 hour before or 2 hours after eating.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure one week after starting this medication, and tell your doctor if it hasn't improved.
  • Requires routine blood tests to check how your kidneys are working.
  • Don't take if you are pregnant.
  • Can cause dizziness in the first few days.
Learn more
More about CaptoprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Capoten (Captopril)?
Worth itNot sureNot worth it
More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Altace (Ramipril)?
Worth itNot sureNot worth it