Compare Captopril vs. Altace

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Capoten
(Captopril)

Altace
(Ramipril)

Lowers blood pressure. Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.Lowers blood pressure. Altace (Ramipril) is a good blood pressure-lowering medicine that protects kidney function. Easy to use if you can't swallow whole capsules.
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Reviews & ratings
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3.8190476190476192Captopril
Reviews for Capoten (Captopril)
33%
of people say Capoten (Captopril) is worth it
25%
say it works well
26%
say it's a big hassle

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Side effects
CaptoprilAltace

The Captopril FDA package insert doesn’t have numbers about how common side effects are.

More about Captopril side effects »
  • Low blood pressure 6%
  • Cough 5%
  • Cough increased 4%
  • Dizziness 1%
  • Nausea 1%
  • Fainting 1%
  • Positional low blood pressure 1%
  • Fatigue 1%
  • Vomiting 1%
  • Vertigo 1%
More Altace side effects »
How it works
CaptoprilAltace
Captopril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Altace (Ramipril) is an angiotensin converting enzyme (ACE) inhibitor. By blocking a chemical that usually tightens blood vessels, it makes blood vessels relax. This lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
CaptoprilAltace
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
ACE inhibitor
Prescription only
Available as
CaptoprilAltace
  • Pill
  • Pill
Used for (click to learn more)
CaptoprilAltace
Risk factors for serious side effects
CaptoprilAltace
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    Detailed Capoten (Captopril) risks & warnings »
    • Women of childbearing age
    • History of ACE inhibitor induced cough
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    • History of kidney problems
    Detailed Altace (Ramipril) risks & warnings »
    Pregnancy category
    CaptoprilAltace
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check how your kidneys are working.
    • Altace (Ramipril) has a risk of making your kidneys not work as well. It's important to get blood work done to check your kidney function before starting Altace (Ramipril) and at least yearly after.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    CaptoprilAltace
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • The only ACE inhibitor that comes in a capsule that you can sprinkle in applesauce or water.
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    Downsides and risks
    CaptoprilAltace
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Up to 1 and 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    Tips from our pharmacists for people taking the medication
    CaptoprilAltace
    • Take 1 hour before or 2 hours after eating.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    • Can cause dizziness in the first few days.
    • Check your blood pressure one week after starting this medication, and tell your doctor if it hasn't improved.
    • Requires routine blood tests to check how your kidneys are working.
    • Don't take if you are pregnant.
    • Can cause dizziness in the first few days.
    Learn more
    More about CaptoprilSide effectsReviews & ratingsAlternativesFDA package insert
    More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert