Compare Captopril vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Capoten
(captopril)

Lopressor
(metoprolol tartrate)

Lowers blood pressure. Captopril is a good blood pressure-lowering medicine that protects kidney function, but you have to take it on an empty stomach.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.
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Coupons for Captopril
Best available price for 60 (25mg) tablets of captopril
Coupons for Lopressor
Best available price for 60 (25mg) tablets of lopressor
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.84Captopril
Reviews for Captopril
34%
of people (All ages) say Captopril is worth it
25%
say it works well
25%
say it's a big hassle
106 reviews
Have you used Capoten (captopril)?
Worth itNot sureNot worth it
Reviews for Lopressor
62%
-28% worse vs. Captopril
47%
-22% worse vs. Captopril
15%
-10% worse vs. Captopril
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Side effects
CaptoprilLopressor
  • Rash 7%
  • Flushing 5%
  • Abnormal sense of taste 4%
  • Itching 2%
  • Cough 2%
More Captopril side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
CaptoprilLopressor
Captopril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
CaptoprilLopressor
Prescription onlyPrescription only
Available as
CaptoprilLopressor
  • Pill
  • Pill
Used for
CaptoprilLopressor
Risk factors for serious side effects
CaptoprilLopressor
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Capoten (captopril) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
CaptoprilLopressor
No food related info.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
Kidneys and liver
CaptoprilLopressor
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
No kidneys and liver related info.
Pain
CaptoprilLopressor
No pain related info.
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
Upsides and benefits
CaptoprilLopressor
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
Downsides and risks
CaptoprilLopressor
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when and how you take it. Captopril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
CaptoprilLopressor
  • Take 1 hour before or 2 hours after eating.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or change in taste sensation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
Learn more
More about CaptoprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Capoten (captopril)?
Worth itNot sureNot worth it
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it