Compare Carafate vs. Aciphex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Carafate (Sucralfate)

Aciphex (Rabeprazole)

Prescription only
No information currently available
Treats heartburn and ulcers.

Aciphex (Rabeprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.

No information currently available
  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Aciphex (Rabeprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Aciphex (Rabeprazole) can be taken daily.
No information currently available
  • Taking Aciphex (Rabeprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
Used for
Dosage forms
  • Pill
  • Liquid
  • Extended release
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Side effects
The Carafate (Sucralfate) FDA package insert doesn’t have numbers about how common side effects are.
7possible side effects
  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Vomiting
  • Pain
  • Pharyngitis
See more detailed side effects
Risks and warnings
No information currently available
  • Severe stomach inflammation (atrophic gastritis)

    Helicobacter pylori infection

    ...and 1 more risk factors

  • Severe diarrhea

    Being hospitalized

    ...and 1 more risk factors

  • Broken bones


    ...and 5 more risk factors

See more detailed risks and warnings