Compare Carafate vs. Aciphex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Carafate
(sucralfate)

Aciphex
(rabeprazole)

Coming soon.Treats heartburn and ulcers. Aciphex (Rabeprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.
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Reviews & ratings
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Have you used Carafate (sucralfate)?
Worth itNot sureNot worth it

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Have you used Aciphex (rabeprazole)?
Worth itNot sureNot worth it
Side effects
CarafateAciphex

We haven’t found good data for Carafate side effects.

FDA side effect reports for Carafate »
  • Headache 10%
  • Diarrhea 5%
  • Nausea 5%
  • Abdominal pain 5%
  • Vomiting 4%
  • Sore throat 1%
  • Passing gas 2%
  • Pain 2%
More Aciphex side effects »
How it works
CarafateAciphex
Coming soon.Aciphex (Rabeprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.
Type of medication
CarafateAciphex
Prescription only
Available as
CarafateAciphex
  • Pill
  • Liquid
  • Extended release
Used for
CarafateAciphex
  • Duodenal Ulcer Disease
Risk factors for serious side effects
CarafateAciphex
Coming soon.
    • Helicobacter pylori infection
    • Autoimmune disease
    • Being hospitalized
    • Antibiotic use
    • Osteoporosis
    • Age 50 or older
    • Using high medication doses
    • Long-term therapy (1 year or more)
    • Smoking
    • Use of other medications that weaken bones
      Detailed Aciphex (rabeprazole) risks & warnings »
      Pregnancy

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Interactions
      CarafateAciphex
      No interactions related info.
      • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
      Food
      CarafateAciphex
      No food related info.
      • Take Aciphex (Rabeprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
      Pain
      CarafateAciphex
      No pain related info.
      • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
      Upsides and benefits
      CarafateAciphex
      Coming soon
      • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
      • Lasts longer than other similar stomach medicines. Most people take it once a day.
      • Your body won't develop a tolerance to Aciphex (Rabeprazole), so it'll work the same way as long as you need to keep taking it.
      • Once heartburn symptoms are treated, a low dose of Aciphex (Rabeprazole) can be taken daily.
      Downsides and risks
      CarafateAciphex
      Coming soon
      • Taking Aciphex (Rabeprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
      • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
      • There's no generic version available, so it can be expensive.
      Tips from our pharmacists for people taking the medication
      CarafateAciphex
      Coming soon
      • Can take a few days to start working.
      • Take Aciphex (Rabeprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
      • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
      • Aciphex (Rabeprazole) can lower the amount of magnesium in your body. Initial and follow-up blood tests may be needed before starting Aciphex (Rabeprazole).
      Learn more
      More about CarafateSide effectsReviews & ratingsFDA package insert
      Have you used Carafate (sucralfate)?
      Worth itNot sureNot worth it
      More about AciphexSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Aciphex (rabeprazole)?
      Worth itNot sureNot worth it