Compare Carafate vs. pantoprazole

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Carafate (Sucralfate)

Protonix (pantoprazole)

Prescription only
No information currently available
Treats heartburn and excess release of stomach acid.

Protonix (pantoprazole) is usually only taken once a day for long-lasting heartburn relief, but it can increase your risk of bone fractures if you've used it for a long time.

5.1/ 7 average rating with 584 reviewsforpantoprazole
Upsides
No information currently available
  • Most people can take Protonix (pantoprazole) without any noticeable day-to-day side effects.
  • Protonix (pantoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
  • You can take it with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
  • Can be used in children age 5 or older.
Downsides
No information currently available
  • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
  • Needs to be taken every single day for a certain period of time to be effective.
  • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
  • Only available as a prescription medicine, not over the counter.
  • Can lower the magnesium level in your body so you may need to take a supplement for it.
Used for
  • Duodenal ulcer disease
  • Active Duodenal ulcer disease
  • Maintenance
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Packet
Price
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$29.76
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$9.35
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Reviews
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584 
68%
think this treatment is worth it
51%
think this treatment works well
13%
think this treatment is a hassle

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Side effects
The Carafate (Sucralfate) FDA package insert doesn’t have numbers about how common side effects are.
8possible side effects
  • Headache
    12%
  • Diarrhea
    9%
  • Nausea
    7%
  • Stomach pain
    6%
  • Vomiting
    4%
  • Gas
    4%
  • Dizziness
    3%
  • Joint pain
    3%
See more detailed side effects
Risks and warnings
No information currently available
  • Weakened bones

    Using multiple daily doses and/or for 1 year or longer

    ...and 2 more risk factors

  • Severe diarrhea

    People who are being treated in the hospital

  • Lupus

    People with lupus

  • Low Vitamin B-12 level

    Taking Protonix (pantoprazole) for more than 3 years

  • Low magnesium level

    Diuretics (water pills)

    ...and 1 more risk factors

See more detailed risks and warnings