Compare Carafate vs. Pantoprazole

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Carafate
(Sucralfate)

Protonix
(Pantoprazole)

Coming soon.Treats heartburn and stomach ulcers. Protonix (Pantoprazole) gives you long-lasting heartburn relief. Choose the cheapest proton pump inhibitor because they all work equally well for heartburn.
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Reviews & ratings
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Reviews for Protonix (Pantoprazole)
69%
+69% vs. Carafate (Sucralfate)
51%
+51% vs. Carafate (Sucralfate)
13%
13% vs. Carafate (Sucralfate)
Side effects
CarafatePantoprazole

We haven’t found good data for Carafate side effects.

FDA side effect reports for Carafate »

We haven’t found good data for Pantoprazole side effects.

FDA side effect reports for Pantoprazole »
How it works
CarafatePantoprazole
Coming soon.Protonix (Pantoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.
Type of medication
CarafatePantoprazole
Coming soon.
Acid reducer
Proton pump inhibitor
Prescription only
Available as
CarafatePantoprazole
  • Pill
  • Liquid
  • Extended release
Used for (click to learn more)
CarafatePantoprazole
  • Duodenal ulcer disease
Risk factors for serious side effects
CarafatePantoprazole
Coming soon.
    • Helicobacter pylori infection
    • Autoimmune disease
    • Osteoporosis
    • Age 50 or older
    • Using high medication doses
    • Long-term therapy (1 year or more)
    • Smoking
    • Use of other medications that weaken bones
        Detailed Protonix (Pantoprazole) risks & warnings »
        Pregnancy category
        CarafatePantoprazole
        BFDA pregnancy category (Probably safe)

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        See the FDA package insert
        BFDA pregnancy category (Probably safe)

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        See the FDA package insert
        Alcohol
        No specific alcohol-related info.No specific alcohol-related info.
        Food
        No specific food-related info.
        • Take with or without food.
        • Take the oral suspension 30 minutes before a meal mixed only with applesauce or apple juice. Follow instructions carefully.
        Kidneys and liver
        No specific kidneys and liver-related info.No specific kidneys and liver-related info.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        No specific sleep-related info.No specific sleep-related info.
        Weight
        No specific weight-related info.No specific weight-related info.
        Upsides and benefits
        CarafatePantoprazole
        Coming soon.
        • Most people can take Pantoprazole without any noticeable day-to-day side effects.
        • Pantoprazole lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
        • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
        • In studies it was better than a placebo (sugar pill) and as good as other proton pump inhibitors at treating heartburn.
        • Available as both a generic and over-the-counter option, so it's pretty affordable.
        Downsides and risks
        CarafatePantoprazole
        Coming soon.
        • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
        • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
        • Can cause low levels of magnesium in the blood. You might need to take a magnesium supplement if you use Pantoprazole long-term.
        • Can be expensive. Other alternatives are usually cheaper than Pantoprazole.
        • Less risk of drug interactions with Pantoprazole than with other proton pump inhibitors.
        Tips from our pharmacists for people taking the medication
        CarafatePantoprazole
        Coming soon.
        • Take with or without food.
        • Swallow tablets whole; don't split, crush, or chew.
        • Take the oral suspension 30 minutes before a meal mixed only with applesauce or apple juice. Follow instructions carefully.
        • When using Pantoprazole long-term, take a calcium citrate with vitamin D supplement daily to prevent bone loss. Be sure it's calcium citrate because it works the best when using a proton pump inhibitor.
        • Get a blood test for your magnesium level once a year; you may need a magnesium supplement while using Pantoprazole.
        • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Pantoprazole.
        Learn more
        More about CarafateSide effectsReviews & ratingsFDA package insert
        More about PantoprazoleSide effectsReviews & ratingsAlternativesFDA package insert