Compare Carafate vs. Pepcid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Carafate
(Sucralfate)

Pepcid
(Famotidine)

Coming soon.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
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Reviews & ratings
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Have you used Carafate (Sucralfate)?
Worth itNot sureNot worth it
Reviews for Pepcid (Famotidine)
75%
+75% vs. Carafate (Sucralfate)
41%
+41% vs. Carafate (Sucralfate)
8%
8% vs. Carafate (Sucralfate)
853 reviews
Have you used Pepcid (Famotidine)?
Worth itNot sureNot worth it
Side effects
CarafatePepcid

We haven’t found good data for Carafate side effects.

FDA side effect reports for Carafate »

The Pepcid FDA package insert doesn’t have numbers about how common side effects are.

More about Pepcid side effects »
How it works
CarafatePepcid
Coming soon.Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.
Type of medication
CarafatePepcid
Coming soon.
Acid reducer
Histamine blocker
Prescription or OTC
Available as
CarafatePepcid
  • Pill
  • Liquid
  • Pill
  • Chewable tablet
  • Liquid
Used for (click to learn more)
CarafatePepcid
  • Duodenal ulcer disease
Risk factors for serious side effects
CarafatePepcid
  • Current kidney disease
Detailed risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Interactions
CarafatePepcid
No interactions related info.
  • Few drug interactions.
Kidneys and liver
CarafatePepcid
No kidneys and liver related info.
  • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
  • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
Upsides and benefits
CarafatePepcid
Coming soon
  • Most people can take Famotidine without any noticeable day-to-day side effects.
  • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
  • Few drug interactions.
Downsides and risks
CarafatePepcid
Coming soon
  • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
  • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
  • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
Tips from our pharmacists for people taking the medication
CarafatePepcid
Coming soon
  • Short-term treatment of ulcers and acid reflux.
Learn more
More about CarafateSide effectsReviews & ratingsFDA package insert
Have you used Carafate (Sucralfate)?
Worth itNot sureNot worth it
More about PepcidSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pepcid (Famotidine)?
Worth itNot sureNot worth it