Compare Carafate vs. Pepcid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Carafate
(Sucralfate)

Pepcid
(Famotidine)

Coming soon.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
Reviews & ratings
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Have you used Carafate (Sucralfate)?
Worth itNot sureNot worth it
Reviews for Pepcid
75%
-75% worse vs. Carafate
41%
-41% worse vs. Carafate
8%
+8% better vs. Carafate
853 reviews
Have you used Pepcid (Famotidine)?
Worth itNot sureNot worth it
Side effects
CarafatePepcid

We haven’t found good data for Carafate side effects.

FDA side effect reports for Carafate »
  • Diarrhea 2%
  • Headache 5%
More Pepcid side effects »
How it works
CarafatePepcid
Coming soon.Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.
Type of medication
CarafatePepcid
Lower-cost generic availablePrescription or OTCLower-cost generic available
Available as
CarafatePepcid
  • Pill
  • Liquid
  • Pill
  • Chewable tablet
  • Liquid
Used for
CarafatePepcid
  • Duodenal Ulcer Disease
Risk factors for serious side effects
CarafatePepcid
    Coming soon.
    • Current kidney disease
    Detailed Pepcid (Famotidine) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Interactions
    CarafatePepcid
    No interactions related info.
    • Few drug interactions.
    Kidneys and liver
    CarafatePepcid
    No kidneys and liver related info.
    • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    Upsides and benefits
    CarafatePepcid
    Coming soon
    • Most people can take Famotidine without any noticeable day-to-day side effects.
    • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Few drug interactions.
    Downsides and risks
    CarafatePepcid
    Coming soon
    • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
    • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    Tips from our pharmacists for people taking the medication
    CarafatePepcid
    Coming soon
    • Short-term treatment of ulcers and acid reflux.
    Learn more
    More about CarafateSide effectsReviews & ratingsFDA package insert
    Have you used Carafate (Sucralfate)?
    Worth itNot sureNot worth it
    More about PepcidSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Pepcid (Famotidine)?
    Worth itNot sureNot worth it