Compare carbidopa / levodopa / entacapone vs. Duopa
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Stalevo (carbidopa / levodopa / entacapone) is a good choice for Parkinson's disease, especially when carbidopa/levodopa starts losing its effect.
Duopa (carbidopa / levodopa) pumps carbidopa/levodopa into your body throughout the day. It is reserved for advanced Parkinson's disease when your symptoms become more frequent than the dosing of your tablets.
- It combines three medicines into one pill so you don't have to take so many pills daily.
- Stalevo (carbidopa / levodopa / entacapone) is available as a generic.
- Duopa (carbidopa / levodopa) allows you to have better control of your symptoms than oral tablets, especially in later stages of Parkinson's disease.
- You would first start by taking Stalevo (carbidopa / levodopa / entacapone) as two different pills, carbidopa/levodopa and entacapone, before you get switched over to Stalevo (carbidopa / levodopa / entacapone).
- It's less customizable since there are only a few fixed combinations available.
- Given via pump so you'll need to have a procedure to attach the pump to your body.
- You'll need to take good care of the pump so that it doesn't get disconnected or infected.
- Duopa (carbidopa / levodopa) only lasts for 16 hours. You may need to take an extra dose of carbidopa/levodopa as tablet for nighttime control.
- You need to keep Duopa (carbidopa / levodopa) in a fridge, but it should sit at room temperature 20 minutes before infusion.
- Difficulty controlling movements25%
- Muscle spasm10%
- Changes in urine color10%
- Discolored urine10%
- Muscle rigidity9%
- Abdominal pain8%
- Problems with J-tube56%
- Redness and swelling at the J-tube site19%
- Difficulty controlling movements14%
- Discharge at the J-tube site11%
- Swelling in the arms and legs8%
- High blood pressure8%
- Flu and cold8%
- Stomach bleeding
History of stomach ulcers
- Stomach problems
Surgery to place the J-tube
- Falling asleep during the day
Taking other medicines for Parkinson's
- High fever and confusion
Stopping Duopa (carbidopa / levodopa) suddenly
- Lack of impulse control
Taking other medicines for Parkinson's disease