Compare carbidopa / levodopa extended release vs. Emsam

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sinemet CR
(carbidopa / levodopa extended release)

Eldepryl
(selegiline)

Treats Parkinson's disease. Sinemet CR (carbidopa / levodopa extended release) is the first choice treatment for Parkinson's disease.Coming soon.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
No pricing data for this drug at this filter setting. Try searching onGoodRx
Coupons for Emsam
Best available price for 60 (5mg) tablets of selegiline
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Sinemet CR (carbidopa / levodopa extended release)
Not enough review data. Review it!
of people (All ages) say Sinemet CR (carbidopa / levodopa extended release) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Sinemet CR (carbidopa / levodopa extended release)?
Worth itNot sureNot worth it
Reviews for Eldepryl (selegiline)
Not enough review data. Review it!
Same vs. Sinemet CR (carbidopa / levodopa extended release)
Not enough review data. Review it!
Same vs. Sinemet CR (carbidopa / levodopa extended release)
Not enough review data. Review it!
-80% worse vs. Sinemet CR (carbidopa / levodopa extended release)
Have you used Eldepryl (selegiline)?
Worth itNot sureNot worth it
Side effects
carbidopa / levodopa extended releaseEmsam
  • Difficulty controlling movements 17%
  • Nausea 6%
  • Hallucinations 4%
  • Confusion 4%
  • Dizziness 3%
  • Low mood disorder 2%
  • Urinary tract infection 2%
  • Back pain 2%
  • Unusual dreams 2%
  • Muscle spasms 2%
More carbidopa / levodopa extended release side effects »

We haven’t found good data for Emsam side effects.

FDA side effect reports for Emsam »
How it works
carbidopa / levodopa extended releaseEmsam
Sinemet CR (carbidopa / levodopa extended release) is a combination of carbidopa and levodopa that is released in your body over time. Carbidopa prevents breakdown of levodopa so that levodopa can then, enter the brain and relieve symptoms of Parkinson's disease.Coming soon.
Type of medication
carbidopa / levodopa extended releaseEmsam
Prescription only
Available as
carbidopa / levodopa extended releaseEmsam
  • Extended release
  • Pill
  • Patch
Used for
carbidopa / levodopa extended releaseEmsam
  • Major Depressive Disorder
Risk factors for serious side effects
carbidopa / levodopa extended releaseEmsam
  • Taking other medicines for Parkinson's
  • Stopping Sinemet CR (carbidopa / levodopa extended release) suddenly
  • Taking other medicines for Parkinson's disease
Detailed Sinemet CR (carbidopa / levodopa extended release) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Upsides and benefits
    carbidopa / levodopa extended releaseEmsam
    • Sinemet CR (carbidopa / levodopa extended release) is released over a long period of time in your body and can allow you to take fewer pills less frequently.
    Coming soon
    Downsides and risks
    carbidopa / levodopa extended releaseEmsam
    • Sinemet CR (carbidopa / levodopa extended release) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Your saliva, sweat and urine may have dark color and stain your clothing while taking Sinemet CR (carbidopa / levodopa extended release).
    • Sinemet CR (carbidopa / levodopa extended release) will lose its effect over time. If you notice it wearing off sooner than you'd like, talk to your doctor.
    • Sinemet CR (carbidopa / levodopa extended release) may cause unusual cravings in some people.
    Coming soon
    Tips from our pharmacists for people taking the medication
    carbidopa / levodopa extended releaseEmsam
    • Sinemet CR (carbidopa / levodopa extended release) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Your saliva, sweat and urine may have dark color and stain your clothing while taking Sinemet CR (carbidopa / levodopa extended release).
    • Take Sinemet CR (carbidopa / levodopa extended release) 30-60 minutes before a meal so that your body can properly absorb it. Don't eat too much high protein foods (meat, milk, cheese or nuts) because doing so can prevent it from getting absorbed into your body.
    • Sinemet CR (carbidopa / levodopa extended release) may cause unusual cravings in some people.
    Coming soon
    Learn more
    More about carbidopa / levodopa extended releaseSide effectsAlternativesFDA package insert
    Have you used Sinemet CR (carbidopa / levodopa extended release)?
    Worth itNot sureNot worth it
    More about EmsamSide effectsReviews & ratingsFDA package insert
    Have you used Eldepryl (selegiline)?
    Worth itNot sureNot worth it