Compare carbidopa / levodopa vs. Dostinex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sinemet
(carbidopa / levodopa)

Dostinex
(cabergoline)

Treats Parkinson's disease. Sinemet (carbidopa / levodopa) is the first choice treatment for Parkinson's disease.Coming soon.
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Prices and coupon for 90 (25mg/100mg) tablets of carbidopa / levodopa
Coupons for
Prices and coupon for 8 (0.5mg) tablets of cabergoline
Reviews & ratings
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Have you used Sinemet (carbidopa / levodopa)?
Worth itNot sureNot worth it

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Have you used Dostinex (cabergoline)?
Worth itNot sureNot worth it
Side effects
carbidopa / levodopaDostinex

The carbidopa / levodopa FDA package insert doesn’t have numbers about how common side effects are.

More about carbidopa / levodopa side effects »

We haven’t found good data for Dostinex side effects.

FDA side effect reports for Dostinex »
How it works
carbidopa / levodopaDostinex
Sinemet (carbidopa / levodopa) is a combination of carbidopa and levodopa. Carbidopa prevents breakdown of levodopa allowing it to enter the brain and relieve symptoms of Parkinson's disease.Coming soon.
Type of medication
carbidopa / levodopaDostinex
Prescription only
Available as
carbidopa / levodopaDostinex
  • Pill
  • Dissolving tablet
  • Pill
Used for
carbidopa / levodopaDostinex
  • Hyperprolactinemia
Risk factors for serious side effects
carbidopa / levodopaDostinex
  • Taking other medicines for Parkinson's
  • Stopping Sinemet (carbidopa / levodopa) suddenly
    • Taking other medicines for Parkinson's disease
      Detailed Sinemet (carbidopa / levodopa) risks & warnings »
      Coming soon.
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Sleep
      carbidopa / levodopaDostinex
      • Can make you very sleepy.
      • Can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
      No sleep related info.
      Upsides and benefits
      carbidopa / levodopaDostinex
      • Sinemet (carbidopa / levodopa) is widely available as a regular pill, a quick dissolving pill or a liquid taken through a feeding tube.
      • Sinemet (carbidopa / levodopa) is available in generic.
      Coming soon
      Downsides and risks
      carbidopa / levodopaDostinex
      • Can make you very sleepy.
      • Can stain your saliva, sweat and urine a dark color.
      • Will lose its effect over time as your disease progresses.
      • May need to be taken several times during day to control symptoms of Parkinson's disease
      • May cause unusual cravings in some people.
      Coming soon
      Tips from our pharmacists for people taking the medication
      carbidopa / levodopaDostinex
      • Can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
      • Can stain your saliva, sweat and urine a dark color.
      • Take Sinemet (carbidopa / levodopa) 30-60 minutes before a meal so that your body can properly absorb it. Don't eat too much high protein foods (meat, milk, cheese or nuts) because doing so can prevent it from getting absorbed into your body.
      • If you notice Sinemet (carbidopa / levodopa) wearing off sooner than you'd like, talk to your doctor. How much and how often you take it may need to be adjusted.
      • Sinemet (carbidopa / levodopa) may cause unusual cravings in some people.
      Coming soon
      Learn more
      More about carbidopa / levodopaSide effectsAlternativesFDA package insert
      Have you used Sinemet (carbidopa / levodopa)?
      Worth itNot sureNot worth it
      More about DostinexSide effectsReviews & ratingsFDA package insert
      Have you used Dostinex (cabergoline)?
      Worth itNot sureNot worth it