Compare carbidopa / levodopa vs. Mirapex
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Sinemet (carbidopa / levodopa) is the first choice treatment for Parkinson's disease.
Mirapex (Pramipexole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.
- Sinemet (carbidopa / levodopa) is widely available as a regular pill, a quick dissolving pill or a liquid taken through a feeding tube.
- Sinemet (carbidopa / levodopa) is available in generic.
- In studies, Mirapex (Pramipexole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
- Mirapex (Pramipexole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
- Is effective for treating restless leg syndrome.
- Available in a short-acting and a long-acting form.
- Can make you very sleepy.
- Can stain your saliva, sweat and urine a dark color.
- Will lose its effect over time as your disease progresses.
- May need to be taken several times during day to control symptoms of Parkinson's disease
- May cause unusual cravings in some people.
- Mirapex (Pramipexole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
- Mirapex (Pramipexole) can cause hallucinations in older people.
- Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
- You can't suddenly stop taking Mirapex (Pramipexole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
- Dissolving tablet
- Extended release
- Postural hypotension53%
- Extrapyramidal syndrome28%
- Accidental injury17%
- Any side effect12%
- Falling asleep during the day
Taking other medicines for Parkinson's
- High fever and confusion
Stopping Sinemet (carbidopa / levodopa) suddenly
- Lack of impulse control
Taking other medicines for Parkinson's disease
- Driving impairment
Taking with alcohol
...and 1 more risk factors
- Low blood pressure
Taking blood pressure-lowering medicines
- Worsening kidney function
Current kidney problems
- Skin cancer
Age 65 years or older