Compare carbidopa vs. Azilect

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lodosyn
(carbidopa)

Azilect
(rasagiline)

Treats Parkinson's disease when given with levodopa. Lodosyn (carbidopa) enhances the effect of levodopa. It cannot relieve symptoms of Parkinson's disease when taken by itself.Treats Parkinson's disease. Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.
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Coupons for carbidopa
Best available price for 90 (25mg) tablets of carbidopa
Coupons for Azilect
Best available price for 30 (1mg) tablets of rasagiline
Reviews & ratings
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Reviews for Lodosyn (carbidopa)
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of people (All ages) say Lodosyn (carbidopa) is worth it
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say it works well
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say it's a big hassle
Have you used Lodosyn (carbidopa)?
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Reviews for Azilect (rasagiline)
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Same vs. Lodosyn (carbidopa)
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Same vs. Lodosyn (carbidopa)
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Same vs. Lodosyn (carbidopa)
Have you used Azilect (rasagiline)?
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Side effects
carbidopaAzilect

We haven’t found good data for carbidopa side effects.

FDA side effect reports for carbidopa »
  • Difficulty controlling movement 8%
  • Headache 2%
  • Accidental injury 7%
  • Nausea 4%
  • Falls 3%
  • Low blood pressure 6%
  • Constipation 4%
  • Weight loss 6%
  • Joint pain 4%
  • Diarrhea 3%
More Azilect side effects »
How it works
carbidopaAzilect
Lodosyn (carbidopa) is a decarboxylase inhibitor that allows levodopa to enter the brain and relieve symptoms of Parkinson's disease.Azilect (rasagiline) is a monoamine oxidase inhibitor. It increases the amount of dopamine in the brain, which helps those with Parkinson's disease gain better control their movements.
Type of medication
carbidopaAzilect
Prescription only
Prescription only
Available as
carbidopaAzilect
  • Pill
  • Pill
Used for
carbidopaAzilect
Risk factors for serious side effects
carbidopaAzilect
    Detailed Lodosyn (carbidopa) risks & warnings »
    • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    Detailed Azilect (rasagiline) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Upsides and benefits
    carbidopaAzilect
    • Extra doses of Lodosyn (carbidopa) allows you to get more out of levodopa, especially in later stages of the disease.
    • It is available in a combination pill with levodopa once you find the right dose that works for you.
    • Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
    • Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
    • Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
    Downsides and risks
    carbidopaAzilect
    • Your doctor may need to change the dose of Lodosyn (carbidopa) frequently before finding the right dose.
    • It can cause unusual cravings and changes in behavior in some people.
    Tips from our pharmacists for people taking the medication
    carbidopaAzilect
    • Lodosyn (carbidopa) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Your saliva, sweat and urine may have dark color and stain your clothing while taking Lodosyn (carbidopa).
    • Take Lodosyn (carbidopa) 30-60 minutes before a meal so that your body can properly absorb it. Don't eat too much high protein foods (meat, milk, cheese or nuts) because doing so can prevent it from getting absorbed into your body.
    • Lodosyn (carbidopa) doesn't work when taken by itself. Don't stop taking your other medicines for Parkinson's disease.
    • Lodosyn (carbidopa) may cause unusual cravings in some people.
    • Azilect (rasagiline) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Watch how much cheese, soy sauce or smoked meats you eat. Eating too much of these foods while on Azilect (rasagiline) can cause an unsafe rise in blood pressure.
    • Azilect (rasagiline) can make you dizzy or lightheaded, especially when you suddenly stand up from sitting or laying down.
    • Don't stop taking Azilect (rasagiline) without talking to your doctor first. Stopping it suddenly can cause confusion, stiff muscles and a high fever.
    • Azilect (rasagiline) can prevent many medicines from working properly. Check with your doctor or pharmacist if the way you take your other medicines needs to be changed.
    Learn more
    More about carbidopaSide effectsAlternativesFDA package insert
    Have you used Lodosyn (carbidopa)?
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    More about AzilectSide effectsAlternativesFDA package insert
    Have you used Azilect (rasagiline)?
    Worth itNot sureNot worth it