Compare carbidopa vs. carbidopa / levodopa / entacapone

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Lodosyn (carbidopa)

Prescription only
Treats Parkinson's disease when given with levodopa.

Lodosyn (carbidopa) enhances the effect of levodopa. It cannot relieve symptoms of Parkinson's disease when taken by itself.

Treats Parkinson's disease.

Stalevo (carbidopa / levodopa / entacapone) is a good choice for Parkinson's disease, especially when carbidopa/levodopa starts losing its effect.

  • Extra doses of Lodosyn (carbidopa) allows you to get more out of levodopa, especially in later stages of the disease.
  • It is available in a combination pill with levodopa once you find the right dose that works for you.
  • It combines three medicines into one pill so you don't have to take so many pills daily.
  • Stalevo (carbidopa / levodopa / entacapone) is available as a generic.
  • Your doctor may need to change the dose of Lodosyn (carbidopa) frequently before finding the right dose.
  • You would first start by taking Stalevo (carbidopa / levodopa / entacapone) as two different pills, carbidopa/levodopa and entacapone, before you get switched over to Stalevo (carbidopa / levodopa / entacapone).
  • It's less customizable since there are only a few fixed combinations available.
Used for
Dosage forms
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  • Pill
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Side effects
The Lodosyn (carbidopa) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Difficulty controlling movements
  • Muscle spasm
  • Changes in urine color
  • Discolored urine
  • Muscle rigidity
  • Dizziness
  • Abdominal pain
  • Fatigue
  • Constipation
See more detailed side effects
Risks and warnings