Compare Catapres vs. Neurontin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Catapres
(clonidine)

Neurontin
(gabapentin)

Lowers blood pressure. Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.Treats tingling and burning nerve pain. Neurontin (Gabapentin) is an old seizure disorder medicine that's now used to treat nerve-related pain caused by different conditions.
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Coupons for Catapres
Best available price for 60 (0.1mg) tablets of clonidine
Coupons for Neurontin
Best available price for 90 (300mg) capsules of gabapentin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.27Catapres
Reviews for Catapres
42%
of people (All ages) say Catapres is worth it
33%
say it works well
35%
say it's a big hassle
Have you used Catapres (clonidine)?
Worth itNot sureNot worth it
Reviews for Neurontin
57%
-15% worse vs. Catapres
40%
-7% worse vs. Catapres
19%
-16% worse vs. Catapres
620 reviews
Have you used Neurontin (gabapentin)?
Worth itNot sureNot worth it
Side effects
CatapresNeurontin
  • Redness/itching / pruritis 26%
  • Dry mouth 25%
  • Drowsiness 12%
  • Skin blistering 7%
  • Fatigue 6%
  • Headache 5%
  • Skin or nail darkening 5%
  • Allergic contact sensitization 5%
  • Burning 3%
  • Lack of energy 3%
More Catapres side effects »
  • Dizziness 21%
  • Drowsiness 16%
  • Leg or ankle swelling 6%
  • Muscle weakness 1%
  • Diarrhea 2%
  • Infection 2%
  • Dry mouth 3%
  • Constipation 2%
  • Accidental injury 2%
  • Vomiting 2%
More Neurontin side effects »
How it works
CatapresNeurontin
Catapres (Clonidine) is an alpha-2 agonist. It works in the brain to tell your blood vessels to relax, and it lowers the activity of certain stress hormones. This lowers blood pressure.Neurontin (Gabapentin) is an antiepileptic and nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.
Type of medication
CatapresNeurontin
Prescription onlyPrescription only
Available as
CatapresNeurontin
  • Pill
  • Extended release
  • Patch
  • Pill
  • Oral solution
Used for
CatapresNeurontin
Risk factors for serious side effects
CatapresNeurontin
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Catapres (clonidine) risks & warnings »
  • Children ages 3 to 12
  • Taking with alcohol or drugs
  • Stopping Neurontin (Gabapentin) suddenly
Detailed Neurontin (gabapentin) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
CatapresNeurontin
No food related info.
  • Take the extended-release tablet with food.
Pain
CatapresNeurontin
No pain related info.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
Sleep
CatapresNeurontin
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
Upsides and benefits
CatapresNeurontin
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
Downsides and risks
CatapresNeurontin
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
  • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
Tips from our pharmacists for people taking the medication
CatapresNeurontin
  • Usually taken together with other medicines for better blood pressure control.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • The weekly patch form can have fewer side effects.
  • Don't stop taking this medicine suddenly.
  • Extended release tablet also used to treat ADHD.
  • Side effects are common, but usually manageable.
  • Don't drive while taking Neurontin (Gabapentin) until you know how the medication affects you.
  • Neurontin and generic forms of Gabapentin have the same ingredients as Gralise and Horizant, but are dosed differently. Make sure you know which form you're taking since they are used for different purposes.
  • Take the extended-release tablet with food.
  • Stop taking Neurontin (Gabapentin) slowly over at least one week to avoid getting withdrawal symptoms.
Learn more
More about CatapresSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Catapres (clonidine)?
Worth itNot sureNot worth it
More about NeurontinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Neurontin (gabapentin)?
Worth itNot sureNot worth it