Compare Catapres vs. Zanaflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Catapres (Clonidine)

Prescription only

Zanaflex (tizanidine)

Prescription only
Lowers blood pressure.

Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.

4.3/ 7 average rating with 78 reviewsforCatapres
Relaxes your muscles.

Zanaflex (tizanidine) isn't a first-choice treatment for muscle spasticity. Try other options before using this.

6.0/ 7 average rating with 26 reviewsforZanaflex
Upsides
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
  • Relieves muscle spasticity.
  • Available as a generic.
  • Available in a tablet or capsule form. It also comes in a capsule that can be opened and sprinkled in applesauce for people that can't swallow pills.
Downsides
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • This isn't a first-choice muscle relaxing medication. Other drugs work better and have fewer side effects.
  • Takes over an hour to kick in and only lasts 3 to 6 hours.
  • Zanaflex (tizanidine) can lower blood pressure, so be careful if you are already on a blood pressure medication.
  • Need to be consistent every day in taking this with or without food.
  • Elderly individuals have more side effects when taking Zanaflex (tizanidine).
Used for
Dosage forms
  • Pill
  • Extended release
  • Patch
  • Pill
Price
Lowest price near you
$7
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Lowest price near you
$21.55
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Reviews
78 
42%
think this treatment is worth it
33%
think this treatment works well
35%
think this treatment is a hassle

Have you used Catapres (Clonidine)?

Leave a review
26 
81%
think this treatment is worth it
73%
think this treatment works well
19%
think this treatment is a hassle

Have you used Zanaflex (tizanidine)?

Leave a review
Side effects
10possible side effects
  • Erythema / pruritis
    26%
  • Dry mouth
    25%
  • Drowsiness
    12%
  • Localized vesiculation
    7%
  • Fatigue
    6%
  • Headache
    5%
  • Allergic contact sensitization
    5%
  • Hyperpigmentation
    5%
  • Lethargy
    3%
  • Sedation
    3%
See more detailed side effects
10possible side effects
  • Dry mouth
    49%
  • Sleepiness
    48%
  • Weakness
    41%
  • Dizziness
    16%
  • Urinary tract infection
    10%
  • General infection
    6%
  • Liver test abnormality
    6%
  • Constipation
    4%
  • Vomiting
    3%
  • Speech disorder
    3%
See more detailed side effects
Risks and warnings
  • Withdrawal

    Sudden discontinuation of medicine

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Low heart rate (bradycardia)

    Age 65 years or older

    ...and 1 more risk factors

See more detailed risks and warnings
  • Liver damage

    Taking maximum doses of Zanaflex (tizanidine)

  • Dizziness and low blood pressure

    Age 65 years or older

    ...and 1 more risk factors

  • Sleepiness and driving impairment

    Taking other medications that also cause sleepiness

    ...and 3 more risk factors

  • Withdrawal side effects

    Stopping Zanaflex (tizanidine) suddenly

See more detailed risks and warnings