Compare Celebrex vs. Indocin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celebrex (Celecoxib)

Prescription only

Indocin (indomethacin)

Prescription only
Relieves pain and inflammation.

Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.

4.6/ 7 average rating with 550 reviewsforCelebrex
Treats pain and swelling.

Indocin (indomethacin) works well for mild to moderate pain and swelling, but it shouldn't be used long-term since it has some serious side effects.

5.8/ 7 average rating with 26 reviewsforIndocin
Upsides
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
  • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
  • Lasts longer than Ibuprofen.
  • Effective option to relieve mild to moderate pain and swelling.
  • Treats inflammation problems, such as rheumatoid arthritis, osteoarthritis, and acute gout attacks.
  • In studies, Indocin (indomethacin) was more effective than Tylenol for treating osteoarthritis pain.
  • It works as well as Celebrex for treating an acute gout attacks.
  • Available in capsules, long-acting capsules, suppositories, and as a suspension. All forms, except the suspension, are available as generic medications.
Downsides
  • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Indocin (indomethacin) can cause serious heart and stomach problems. The risk goes up the longer you take it, but problems can happen at any time. Don't take Indocin (indomethacin) any longer than your doctor recommends.
  • Indocin (indomethacin) raises your risk of bleeding, especially when taken with other blood-thinning medicines.
  • There are similar medicines that you don't have to take as often and can work just as well.
  • Not a good choice if you have kidney, liver, or stomach problems.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
  • Liquid
  • Suppository
Price
Lowest price near you
$25.05
Find instant savings
Lowest price near you
$5
Find instant savings
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
550 
57%
think this treatment is worth it
38%
think this treatment works well
14%
think this treatment is a hassle

Have you used Celebrex (Celecoxib)?

Leave a review
26 
73%
think this treatment is worth it
77%
think this treatment works well
23%
think this treatment is a hassle

Have you used Indocin (indomethacin)?

Leave a review
Side effects
The Celebrex (Celecoxib) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • Nausea
    33%
  • Swelling after surgery
    22%
  • Headache
    14%
  • Dizziness
    14%
  • Bleeding after surgery
    11%
  • Vomiting
    10%
  • Constipation
    5%
  • Itchy skin
    3%
  • Diarrhea
    3%
  • Lightheadedness
    3%
See more detailed side effects
Risks and warnings
  • Heart attack and stroke

    Long-term use

    ...and 2 more risk factors

  • Stomach bleeding

    Age 65 or older

    ...and 1 more risk factors

  • Increased blood pressure

    History of high blood pressure

    ...and 1 more risk factors

  • Increased swelling (edema) and fluid retention

    History of heart failure

  • Asthma attacks

    History of asthma

  • Lowered kidney function

    Kidney Disease

    ...and 6 more risk factors

  • Harm to unborn babies

    Late pregnancy (more than 30 weeks)

See more detailed risks and warnings
  • Heart attack or stroke

    History of heart disease

    ...and 2 more risk factors

  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 1 more risk factors

  • Harm to fetus (unborn baby)

    Women of childbearing age

  • Serious allergic reactions

    Asthma

    ...and 1 more risk factors

  • Worsening kidney or liver function

    Current kidney problems

    ...and 1 more risk factors

  • Bleeding or bruising

    Blood-thinning medicines

    ...and 1 more risk factors

See more detailed risks and warnings