Compare Celebrex vs. Percocet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celebrex (Celecoxib)

Prescription only
Relieves pain and inflammation.

Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.

4.6/ 7 average rating with 550 reviewsforCelebrex
Treats moderate to severe pain.

Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.

5.2/ 7 average rating with 1399 reviewsforPercocet
Upsides
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
  • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
  • Lasts longer than Ibuprofen.
  • Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
  • Provides quick relief for moderate to severe pain to improve quality of life.
  • Generally considered stronger than Norco or other combination pain medicine for treating pain.
  • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
  • Lower rates of misuse compared to pure opioid medicines.
  • Can help you fall asleep easier.
Downsides
  • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
  • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
  • The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
  • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
  • Avoid alcohol.
Used for
Dosage forms
  • Pill
  • Pill
  • Oral solution
Price
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$25.05
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Reviews
550 
57%
think this treatment is worth it
38%
think this treatment works well
14%
think this treatment is a hassle

Have you used Celebrex (Celecoxib)?

Leave a review
1399 
70%
think this treatment is worth it
49%
think this treatment works well
15%
think this treatment is a hassle

Have you used Percocet (Oxycodone / Acetaminophen)?

Leave a review
Side effects
The Celebrex (Celecoxib) FDA package insert doesn’t have numbers about how common side effects are.
The Percocet (Oxycodone / Acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack and stroke

    Long-term use

    ...and 2 more risk factors

  • Stomach bleeding

    Age 65 or older

    ...and 1 more risk factors

  • Increased blood pressure

    History of high blood pressure

    ...and 1 more risk factors

  • Increased swelling (edema) and fluid retention

    History of heart failure

  • Asthma attacks

    History of asthma

  • Lowered kidney function

    Kidney Disease

    ...and 6 more risk factors

  • Harm to unborn babies

    Late pregnancy (more than 30 weeks)

See more detailed risks and warnings
  • Death from liver failure

    Current liver disease

    ...and 2 more risk factors

  • Death from lack of oxygen to the body (respiratory depression)

    Age 65 or greater

    ...and 3 more risk factors

  • Driving impairment

    Taking with alcohol

    ...and 2 more risk factors

  • Tolerance and dependence

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Neonatal withdrawal syndrome

    Long-term use of opioids in mother

    ...and 1 more risk factors

  • Death from overdose (extended-release tablet)

    Children age 18 and younger

    ...and 2 more risk factors

  • Low blood pressure

    Age 65 years or older

    ...and 1 more risk factors

See more detailed risks and warnings