Compare Celebrex vs. Plavix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celebrex
(celecoxib)

Plavix
(clopidogrel)

Relieves pain and inflammation. Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.Prevents blood clots. Plavix (clopidogrel) is a cheap, generically available blood thinner that protects you from clots after you've had a heart attack or surgery.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.59Celebrex
Reviews for Celebrex
57%
of people (All ages) say Celebrex is worth it
38%
say it works well
14%
say it's a big hassle
550 reviews
Have you used Celebrex (celecoxib)?
Worth itNot sureNot worth it
Reviews for Plavix
59%
-2% worse vs. Celebrex
49%
-11% worse vs. Celebrex
16%
+2% better vs. Celebrex
343 reviews
Have you used Plavix (clopidogrel)?
Worth itNot sureNot worth it
Side effects
CelebrexPlavix

We haven’t found good data for Celebrex side effects.

FDA side effect reports for Celebrex »
  • Minor bleeding 3%
  • Major bleeding 1%
More Plavix side effects »
How it works
CelebrexPlavix
Celebrex (Celecoxib) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Plavix (clopidogrel) is an antiplatelet blood thinner. It stops platelets in your blood from clumping together which makes it harder for them to form clots.
Type of medication
CelebrexPlavix
Prescription onlyPrescription only
Available as
CelebrexPlavix
  • Pill
  • Pill
Used for
CelebrexPlavix
Risk factors for serious side effects
CelebrexPlavix
  • Long-term use
  • History of heart disease
  • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Age 65 or older
  • History of GI bleed or peptic ulcer disease
Detailed Celebrex (celecoxib) risks & warnings »
  • Taking Prilosec or Nexium
  • People with certain genes that make Plavix (clopidogrel) less effective
  • History of stomach bleeding
  • Taking other medicines that increase the levels of Plavix (clopidogrel) in your body
  • Taking other blood thinners or medicines that increase the risk of bleeding
Detailed Plavix (clopidogrel) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
CelebrexPlavix
  • Take it with a meal or a snack to prevent an upset stomach.
No food related info.
Kidneys and liver
CelebrexPlavix
  • Celebrex (Celecoxib), and similar medications in the NSAID family, can cause lower kidney function or cause permanent kidney damage. You're at higher risk for this if you've a history of kidney disease, heart failure, and liver disease. Taking Diuretic, ACE inhibitor, or Angiotensin Receptor Blocker (ARB) medications also increases your risk. If you are 65 or older you're also at a higher risk for these types of kidney problems.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
No kidneys and liver related info.
Pain
CelebrexPlavix
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
No pain related info.
Upsides and benefits
CelebrexPlavix
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
  • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
  • Lasts longer than Ibuprofen.
  • Plavix (clopidogrel) can help lower your risk of getting a stroke or heart attack.
  • You only need to take it once a day.
  • A genetic test is available to determine whether Plavix (clopidogrel) will be an effective treatment option for you.
Downsides and risks
CelebrexPlavix
  • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Raises your risk of bleeding and bruising, which can be serious and life-threatening.
  • May not be safe to be taken with many other medicines or supplements.
  • If you've taken too much Plavix (clopidogrel) and you're bleeding, plasma transfusions are required to stop the bleeding.
Tips from our pharmacists for people taking the medication
CelebrexPlavix
  • Starts working in 1 to 3 hours.
  • Take it with a meal or a snack to prevent an upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Thins your blood to prevent clots from forming or getting bigger.
  • Can raise your risk of bleeding or bruising.
  • Take this medicine exactly as told by your doctor.
  • Plavix (clopidogrel) may not be safe to be taken together with some medicines and over-the-counter supplements. Don't start any new medicine without first speaking with your doctor or pharmacist.
  • Let your doctor know right away if you experience a fever, weakness, or unusual bleeding and bruising.
  • You should stop taking Plavix (clopidogrel) at least 5 days before any major surgeries to lower your chances of bleeding.
Learn more
More about CelebrexSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Celebrex (celecoxib)?
Worth itNot sureNot worth it
More about PlavixSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Plavix (clopidogrel)?
Worth itNot sureNot worth it