Compare Celebrex vs. Relafen

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celebrex (Celecoxib)

Prescription only

Relafen (nabumetone)

Prescription only
Relieves pain and inflammation.

Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.

3.4/ 5 average rating with 550 reviewsforCelebrex
Relieves pain and inflammation.

Relafen (nabumetone) works well for relieving pain and inflammation, but may take up to a week to kick in.

Upsides
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
  • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
  • Lasts longer than Ibuprofen.
  • Relafen (nabumetone) is good for relieving pain and inflammation from osteoarthritis and rheumatoid arthritis.
  • Usually taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
  • Relafen (nabumetone) causes less stomach upset and overall side effects than other NSAIDs, like ibuprofen and naproxen.
Downsides
  • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Relafen (nabumetone) does not work as quickly as other NSAIDs.
  • Relafen (nabumetone), like other NSAIDS, is not safe for pregnant women and people who are age 60 or older.
  • Relafen (nabumetone) can cause serious complications including stomach bleeding and kidney problems if taken for a long period of time.
  • The safety and effectiveness of Relafen (nabumetone) for children are not known so they should not take it.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
550 reviews so far
57%
saidit'sworth it
38%
saiditworked well
14%
saidit'sa big hassle

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Side effects
The Celebrex (Celecoxib) FDA package insert doesn’t have numbers about how common side effects are.
3possible side effects
  • Diarrhea
    14%
  • Upset stomach
    13%
  • Stomach pain
    12%
See more detailed side effects
Risks and risk factors
  • Heart attack and stroke
    • Long-term use
    • History of heart disease
    • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Stomach bleeding
    • Age 65 or older
    • History of GI bleed or peptic ulcer disease
  • Increased blood pressure
    • History of high blood pressure
    • Taking water pills (diuretics)
  • Increased swelling (edema) and fluid retention
    • History of heart failure
  • Skin reactions
  • Asthma attacks
    • History of asthma
  • Lowered kidney function
    • Kidney Disease
    • Heart Failure
    • Liver Disease
    • Also taking diuretics
    • Also taking ACE inhibitors
    • Also taking Angiotensin Receptor Blockers (ARBs)
    • Age 65 or older
  • Harm to unborn babies
    • Late pregnancy (more than 30 weeks)
See more detailed risks and warnings
  • Heart attack and stroke
    • History of heart problems
    • Taking Relafen (nabumetone) for a long period of time
  • Stomach bleeding
    • History of stomach bleeding and/or ulcers
    • Age 60 or older
    • Taking aspirin, other NSAIDs, steroids, or blood thinners
    • Drinking alcoholic beverages
    • Smoking
    • Taking the medicine for a long period of time
    • People with poor general health
  • Severe allergic reaction
    • Asthma
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Kidney damage
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking certain high blood pressure medications
    • Age 60 or older
    • Taking the medicine for a long period of time
  • Harm to fetus
    • Pregnant women
    • Women who want to or can become pregnant
  • Heart-related complications
    • Recent heart surgery or heart attack
    • History of high blood pressure
    • History of heart failure
See more detailed risks and warnings