Compare Celebrex vs. Tylenol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celebrex (Celecoxib)

Prescription only
Relieves pain and inflammation.

Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.

4.6/ 7 average rating with 550 reviewsforCelebrex
Relieves pain and fever.

Tylenol Regular Strength (acetaminophen) effectively reduces fever and relieves pain, but it doesn't lower inflammation and swelling.

5.0/ 7 average rating with 1002 reviewsforTylenol
Upsides
  • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Good for treating muscle aches and pains, as well as menstrual cramps.
  • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
  • Lasts longer than Ibuprofen.
  • Works well to relieve pain and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Tylenol Regular Strength (acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin and Advil.
  • Doesn't cause kidney damage and is also safe to use if you have heart problems or if you're pregnant.
  • Tylenol Regular Strength (acetaminophen) has been used for a long time and is generally safe for short-term use.
Downsides
  • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
  • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
  • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
  • Tylenol Regular Strength (acetaminophen) doesn't treat some kinds of pain as well as other medications like Advil.
  • Drinking alcohol while taking Tylenol Regular Strength (acetaminophen) can damage your liver.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen you are taking since it's a very common ingredient in pain and cold combination medicines.
  • Heavy alcohol drinkers and people with liver problems should avoid using Tylenol Regular Strength (acetaminophen) since it can cause serious liver damage.
Used for
Dosage forms
  • Pill
  • Pill
  • Chewable tablet
  • Dissolving tablet
  • Liquid
  • Suppository
  • Injection
Price
Lowest price near you
$25.05
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Lowest price near you
$238.38
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Reviews
550 
57%
think this treatment is worth it
38%
think this treatment works well
14%
think this treatment is a hassle

Have you used Celebrex (Celecoxib)?

Leave a review
1002 
77%
think this treatment is worth it
37%
think this treatment works well
3%
think this treatment is a hassle

Have you used Tylenol Regular Strength (acetaminophen)?

Leave a review
Side effects
The Celebrex (Celecoxib) FDA package insert doesn’t have numbers about how common side effects are.
The Tylenol Regular Strength (acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack and stroke

    Long-term use

    ...and 2 more risk factors

  • Stomach bleeding

    Age 65 or older

    ...and 1 more risk factors

  • Increased blood pressure

    History of high blood pressure

    ...and 1 more risk factors

  • Increased swelling (edema) and fluid retention

    History of heart failure

  • Asthma attacks

    History of asthma

  • Lowered kidney function

    Kidney Disease

    ...and 6 more risk factors

  • Harm to unborn babies

    Late pregnancy (more than 30 weeks)

See more detailed risks and warnings
  • Accidental overdose and death

    Medication administering errors

    ...and 2 more risk factors

  • Liver damage

    Drinking more than 2 alcoholic beverages a day

    ...and 2 more risk factors

See more detailed risks and warnings