Compare Celebrex vs. Voltaren

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celebrex
(Celecoxib)

Voltaren
(Diclofenac Sodium)

Relieves pain and inflammation. Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.Relieves pain and inflammation. Voltaren (Diclofenac Sodium) works well for pain and causes less upset stomach than other NSAIDs.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.5482041587901705Celebrex
Reviews for Celebrex (Celecoxib)
56%
of people say Celebrex (Celecoxib) is worth it
36%
say it works well
13%
say it's a big hassle
Reviews for Voltaren (Diclofenac Sodium)
73%
+17% vs. Celebrex (Celecoxib)
68%
+32% vs. Celebrex (Celecoxib)
9%
+4% vs. Celebrex (Celecoxib)
Side effects
CelebrexVoltaren

We haven’t found good data for Celebrex side effects.

FDA side effect reports for Celebrex »
  • Application site contact dermatitis 29%
  • Application site rash 29%
  • Dry skin (application site) 27%
  • Application site dry skin 15%
  • Application site rash 15%
  • Application site reaction 14%
  • Any side effect 14%
  • Application site exfoliation 11%
  • Application site pruritus 7%
  • Contact dermatitis (application site) 7%
More Voltaren side effects »
How it works
CelebrexVoltaren
Celebrex (Celecoxib) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Voltaren (Diclofenac Sodium) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.
Type of medication
CelebrexVoltaren
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Available as
CelebrexVoltaren
  • Pill
  • Extended release
  • Cream, gel, or ointment
  • Eye drops
Used for (click to learn more)
CelebrexVoltaren
Risk factors for serious side effects
CelebrexVoltaren
  • Long-term use
  • History of heart disease
  • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Age 65 or older
  • History of GI bleed or peptic ulcer disease
  • History of high blood pressure
  • Taking water pills (diuretics)
  • History of heart failure
    • History of asthma
    • Kidney Disease
    • Heart Failure
    • Liver Disease
    • Also taking diuretics
    • Also taking ACE inhibitors
    • Also taking Angiotensin Receptor Blockers (ARBs)
    • Age 65 or older
    • Late pregnancy (more than 30 weeks)
    Detailed Celebrex (Celecoxib) risks & warnings »
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking
    • History of stomach bleeding or ulcers
    • Age 65 years or older
    • Hemophilia
    • von Willebrand's disease
    • Low blood platelet count
    • Also taking an anticoagulant medication
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking diuretics
    • Taking ACE inhibitors or angiotensin receptor blockers (ARBs)
    • Age 65 or older
    • History of high blood pressure
    • Taking water pills (diuretics)
    • Late pregnancy (more than 30 weeks)
    Detailed Voltaren (Diclofenac Sodium) risks & warnings »
    Pregnancy category
    CelebrexVoltaren
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • Take it with a meal or a snack to prevent an upset stomach.
    • If taking Voltaren (Diclofenac Sodium) by mouth, take it with a meal or a snack to prevent an upset stomach.
    Kidneys and liver
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Celebrex (Celecoxib), and similar medications in the NSAID family, can cause lower kidney function or cause permanent kidney damage. You're at higher risk for this if you've a history of kidney disease, heart failure, and liver disease. Taking Diuretic, ACE inhibitor, or Angiotensin Receptor Blocker (ARB) medications also increases your risk. If you are 65 or older you're also at a higher risk for these types of kidney problems.
    • Can lower kidney function or cause permanent kidney damage. These problems are more likely the longer you take it.
    • Can affect your kidneys' ability to work as well.
    • Voltaren (Diclofenac Sodium), and similar medications in the NSAID family, can lower kidney function or cause permanent kidney damage. Taking the lowest dose for the shortest amount of time necessary can lower your risk of kidney problems. It's important to get lab tests to check your kidney function periodically if you use Voltaren (Diclofenac Sodium) for long periods of time.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    CelebrexVoltaren
    • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Good for treating muscle aches and pains, as well as menstrual cramps.
    • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
    • Lasts longer than Ibuprofen.
    • Works well to relieve pain and inflammation from osteoarthritis and rheumatoid arthritis.
    • Good for muscle aches and pains.
    • May treat arthritis pain better than other similar medicines (NSAIDs).
    • Can cause less upset stomach than other NSAIDs like ibuprofen (Advil).
    • It's also available as a gel that you put on your skin. If it's hard for you to swallow pills, this could be a good option.
    • If you're only using the gel, you won't have the same side effects that you would while taking Voltaren (Diclofenac Sodium) by mouth.
    Downsides and risks
    CelebrexVoltaren
    • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
    • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • Can cause serious stomach problems like inflammation, ulcers, and bleeding. The chances that a stomach problem will occur is worse the longer you take this medication, but it can happen at any time while taking it.
    • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
    • Can lower kidney function or cause permanent kidney damage. These problems are more likely the longer you take it.
    Tips from our pharmacists for people taking the medication
    CelebrexVoltaren
    • Starts working in 1 to 3 hours.
    • Take it with a meal or a snack to prevent an upset stomach.
    • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
    • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • If taking Voltaren (Diclofenac Sodium) by mouth, take it with a meal or a snack to prevent an upset stomach.
    • Can cause stomach ulcers, especially if taking it by mouth often.
    • Can make you bruise or bleed more easily. You shouldn't take any other 'blood thinner' medications unless your doctor tells you it's safe.
    • Don't use it the first two weeks after a heart surgery.
    • Can affect your kidneys' ability to work as well.
    • If using the skin (topical) gel, use the dosing card it comes with to make sure you measure the correct dose. You also won't have many of the same side effects that you would if taking Voltaren (Diclofenac Sodium) by mouth.
    Learn more
    More about CelebrexSide effectsReviews & ratingsAlternativesFDA package insert
    More about VoltarenSide effectsReviews & ratingsAlternativesFDA package insert