Compare Celexa vs. Lexapro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celexa
(Citalopram)

Lexapro
(Escitalopram)

Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Improves mood and helps you relax. Lexapro (Escitalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.98Celexa
Reviews for Celexa (Citalopram)
61%
of people (All ages) say Celexa (Citalopram) is worth it
51%
say it works well
16%
say it's a big hassle
520 reviews
Have you used Celexa (Citalopram)?
Worth itNot sureNot worth it
Reviews for Lexapro (Escitalopram)
61%
Same vs. Celexa (Citalopram)
48%
-3% worse vs. Celexa (Citalopram)
15%
+1% better vs. Celexa (Citalopram)
1063 reviews
Have you used Lexapro (Escitalopram)?
Worth itNot sureNot worth it
Side effects
CelexaLexapro
  • Nausea 7%
  • Dry mouth 6%
  • Drowsiness 8%
  • Sleep difficulty 1%
  • Sweating increased 2%
  • Diarrhea 3%
  • Tremor 2%
  • Ejaculation disorder 5%
  • Inflammation inside the nose 1%
  • Indigestion 1%
More Celexa side effects »
  • Nausea 8%
  • Ejaculation disorder 9%
  • Sleep difficulty 5%
  • Diarrhea 3%
  • Dry mouth 1%
  • Drowsiness 4%
  • Inflammation inside the nose 1%
  • Dizziness 2%
  • Flu-like symptomsa-like symptoms 1%
  • Sweating increased 3%
More Lexapro side effects »
How it works
CelexaLexapro
Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Lexapro (Escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.
Type of medication
CelexaLexapro
Prescription only
Prescription only
Available as
CelexaLexapro
  • Pill
  • Oral solution
  • Pill
  • Liquid
Used for
CelexaLexapro
Risk factors for serious side effects
CelexaLexapro
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • History of bipolar disorder
  • At risk for bipolar disorder
  • Stopping Celexa (Citalopram) suddenly
  • Higher dose
  • History of heart problems
  • History of liver problems
  • Older age
  • Taking other blood-thinning drugs
    Detailed Celexa (Citalopram) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • Stopping Lexapro (Escitalopram) suddenly
    • Higher dose
    • History of heart problems
    • History of liver problems
    • Taking other blood-thinning drugs
      • History of bipolar disorder
      • At risk for bipolar disorder
      Detailed Lexapro (Escitalopram) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Food
      CelexaLexapro
      • Take with food to avoid upset stomach.
      • Take with food to avoid upset stomach.
      Kidneys and liver
      CelexaLexapro
      • Not a good option for you if you have heart or liver problems.
      • Not a good option for you if you have heart or liver problems.
      Sex
      CelexaLexapro
      • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
      • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
      Weight
      CelexaLexapro
      • Can cause minor weight gain (1 to 5 pounds).
      • More likely to cause minor weight gain (1 to 5 pounds) than other antidepressants.
      Upsides and benefits
      CelexaLexapro
      • Effective at relieving depression and anxiety symptoms.
      • Causes less sleepiness compared to other antidepressants.
      • Six out of ten people who use an antidepressant for the first time find that it works for them.
      • Effective at relieving depression and anxiety symptoms.
      • Lowers relapse rates of depression.
      • Causes less sleepiness than some other antidepressants.
      • Six out of ten people who use an antidepressant for the first time find that it works for them.
      Downsides and risks
      CelexaLexapro
      • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
      • Can cause minor weight gain (1 to 5 pounds).
      • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
      • Not a good option for you if you have heart or liver problems.
      • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
      • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
      • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
      • More likely to cause minor weight gain (1 to 5 pounds) than other antidepressants.
      • Can cause an irregular heartbeat if you take a high dose (20 mg a day, or more).
      • Not a good option for you if you have heart or liver problems.
      • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
      • The first antidepressant you try doesn't always work, and might have side effects you really don't like. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
      Tips from our pharmacists for people taking the medication
      CelexaLexapro
      • Take with food to avoid upset stomach.
      • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
      • Stop taking it slowly to avoid getting withdrawal symptoms.
      • Tell your doctor if you notice sudden mood changes or unusual thoughts.
      • Take with food to avoid upset stomach.
      • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
      • Stop taking it slowly to avoid getting withdrawal symptoms.
      • Tell your doctor if you notice sudden mood changes or unusual thoughts.
      Learn more
      More about CelexaSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Celexa (Citalopram)?
      Worth itNot sureNot worth it
      More about LexaproSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Lexapro (Escitalopram)?
      Worth itNot sureNot worth it