Compare Celexa vs. Lexapro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celexa
(citalopram)

Lexapro
(escitalopram)

Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Improves mood and helps you relax. Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.98Celexa
Reviews for Celexa
61%
of people (All ages) say Celexa is worth it
51%
say it works well
16%
say it's a big hassle
520 reviews
Have you used Celexa (citalopram)?
Worth itNot sureNot worth it
Reviews for Lexapro
61%
Same vs. Celexa
48%
+3% better vs. Celexa
15%
-1% worse vs. Celexa
1063 reviews
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it
Side effects
CelexaLexapro
  • Nausea 7%
  • Dry Mouth 6%
  • Somnolence 8%
  • Insomnia 1%
  • Sweating Increased 2%
  • Diarrhea 3%
  • Tremor 2%
  • Ejaculation Disorder 5%
  • Rhinitis 1%
  • Dyspepsia 1%
More Celexa side effects »
  • Nausea 8%
  • Insomnia 5%
  • Problems with ejaculation 9%
  • Diarrhea 3%
  • Dry Mouth 1%
  • Somnolence 4%
  • Runny nose 1%
  • Fatigue 3%
  • Dizziness 2%
  • Flu-like symptoms 1%
More Lexapro side effects »
How it works
CelexaLexapro
Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin in the brain which regulates mood.
Type of medication
CelexaLexapro
Prescription onlyPrescription only
Available as
CelexaLexapro
  • Pill
  • Oral solution
  • Pill
  • Liquid
Used for
CelexaLexapro
Risk factors for serious side effects
CelexaLexapro
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • History of bipolar disorder
  • At risk for bipolar disorder
  • Stopping Celexa (Citalopram) suddenly
Detailed Celexa (citalopram) risks & warnings »
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Lexapro (escitalopram) suddenly
  • Taking blood thinners
  • Bipolar disorder
Detailed Lexapro (escitalopram) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
CelexaLexapro
No interactions related info.
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
Food
CelexaLexapro
  • Take with food to avoid upset stomach.
No food related info.
Kidneys and liver
CelexaLexapro
  • Not a good option for you if you have heart or liver problems.
No kidneys and liver related info.
Sex
CelexaLexapro
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
No sex related info.
Weight
CelexaLexapro
  • Can cause minor weight gain (1 to 5 pounds).
  • Can cause a small weight gain of 1-5 pounds.
Upsides and benefits
CelexaLexapro
  • Effective at relieving depression and anxiety symptoms.
  • Causes less sleepiness compared to other antidepressants.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
  • Effective at relieving depression and anxiety symptoms.
  • Lowers the likelihood that your depression will come back.
  • Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
Downsides and risks
CelexaLexapro
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Can cause minor weight gain (1 to 5 pounds).
  • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
  • Not a good option for you if you have heart or liver problems.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
  • Can cause a small weight gain of 1-5 pounds.
  • Lexapro (escitalopram) is not a good option if you have heart or liver problems.
  • The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
Tips from our pharmacists for people taking the medication
CelexaLexapro
  • Take with food to avoid upset stomach.
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • Don't suddenly stop taking DRUG NAME. Talk to your doctor about how to slowly go down in your dose to avoid withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • Like other SSRI medications, it could take up to 8 weeks to see the full effects of Lexapro (escitalopram).
  • Take Lexapro (escitalopram) in the morning since it can keep you up if you take it at night.
Learn more
More about CelexaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Celexa (citalopram)?
Worth itNot sureNot worth it
More about LexaproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lexapro (escitalopram)?
Worth itNot sureNot worth it