Compare Celexa vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Celexa
(Citalopram)

Remeron
(Mirtazapine)

Improves mood and helps you relax. Celexa (Citalopram) is good for treating depression and anxiety. Might be less likely to cause side effects than some antidepressants, but not the best choice for people with heart or liver problems.Improves mood. Remeron (Mirtazapine) is okay for treating depression and good for sleep. More likely to cause weight gain than any other antidepressant.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.98Celexa
Reviews for Celexa (Citalopram)
61%
of people (All ages) say Celexa (Citalopram) is worth it
51%
say it works well
16%
say it's a big hassle
520 reviews
Have you used Celexa (Citalopram)?
Worth itNot sureNot worth it
Reviews for Remeron (Mirtazapine)
45%
-16% worse vs. Celexa (Citalopram)
39%
-12% worse vs. Celexa (Citalopram)
26%
-10% worse vs. Celexa (Citalopram)
152 reviews
Have you used Remeron (Mirtazapine)?
Worth itNot sureNot worth it
Side effects
CelexaRemeron
  • Nausea 7%
  • Dry mouth 6%
  • Drowsiness 8%
  • Sleep difficulty 1%
  • Sweating increased 2%
  • Diarrhea 3%
  • Tremor 2%
  • Ejaculation disorder 5%
  • Inflammation inside the nose 1%
  • Indigestion 1%
More Celexa side effects »
  • Drowsiness 36%
  • Dry mouth 10%
  • Increased appetite 15%
  • Constipation 6%
  • Weight gain 10%
  • Muscle weakness 3%
  • Dizziness 4%
  • Flu syndrome 2%
  • Abnormal dreams 3%
  • Thinking abnormal 2%
More Remeron side effects »
How it works
CelexaRemeron
Celexa (Citalopram) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.Remeron (Mirtazapine) is an atypical antidepressant. It stimulates your body to make certain chemicals in the brain, such as serotonin and norepinephrine, which regulate mood.
Type of medication
CelexaRemeron
Prescription only
Prescription only
Available as
CelexaRemeron
  • Pill
  • Oral solution
  • Pill
  • Dissolving tablet
Used for
CelexaRemeron
Risk factors for serious side effects
CelexaRemeron
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • History of bipolar disorder
  • At risk for bipolar disorder
  • Stopping Celexa (Citalopram) suddenly
  • Higher dose
  • History of heart problems
  • History of liver problems
  • Older age
  • Taking other blood-thinning drugs
    Detailed Celexa (Citalopram) risks & warnings »
    • Age 24 years or younger
    • Using other medications that affect serotonin
    • History of heart problems
    • History of liver problems
    • Higher dose
    • Alcohol
    • Taking other medicines that make you less alert
        Detailed Remeron (Mirtazapine) risks & warnings »
        Pregnancy

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Food
        CelexaRemeron
        • Take with food to avoid upset stomach.
        No food related info.
        Kidneys and liver
        CelexaRemeron
        • Not a good option for you if you have heart or liver problems.
        No kidneys and liver related info.
        Sex
        CelexaRemeron
        • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
        No sex related info.
        Weight
        CelexaRemeron
        • Can cause minor weight gain (1 to 5 pounds).
        • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
        • Can increase appetite and weight.
        • Remeron (Mirtazapine) can increase appetite and cause you to gain weight.
        Upsides and benefits
        CelexaRemeron
        • Effective at relieving depression and anxiety symptoms.
        • Causes less sleepiness compared to other antidepressants.
        • Six out of ten people who use an antidepressant for the first time find that it works for them.
        • Effective at relieving some depression symptoms.
        • Starts to work more quickly than most antidepressants.
        • Might be a good option for people who have insomnia with their depression, because it can make you very sleepy.
        • Good option for people who are underweight or frail, because it can help you gain weight.
        • Six out of ten people who use an antidepressant for the first time find that it works for them.
        Downsides and risks
        CelexaRemeron
        • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
        • Can cause minor weight gain (1 to 5 pounds).
        • Celexa (Citalopram) can cause an irregular heartbeat if you take a high dose (40 mg a day, or more).
        • Not a good option for you if you have heart or liver problems.
        • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24 years.
        • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
        • Not as effective as other medications for depression.
        • More sedating than other antidepressants.
        • More likely to cause minor weight gain (1 to 5 pounds) and raise cholesterol than any other antidepressant.
        • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
        • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
        Tips from our pharmacists for people taking the medication
        CelexaRemeron
        • Take with food to avoid upset stomach.
        • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
        • Stop taking it slowly to avoid getting withdrawal symptoms.
        • Tell your doctor if you notice sudden mood changes or unusual thoughts.
        • Makes you sleepy. Take at bedtime.
        • Can increase appetite and weight.
        • Takes 8 to 12 weeks to see full effects on mood.
        • Stop taking slowly to avoid withdrawal symptoms.
        • Tell your doctor if you notice sudden mood changes or unusual thoughts.
        Learn more
        More about CelexaSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Celexa (Citalopram)?
        Worth itNot sureNot worth it
        More about RemeronSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Remeron (Mirtazapine)?
        Worth itNot sureNot worth it