Compare chloroquine vs. Rituxan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

chloroquine

Prescription only

Rituxan (Rituximab)

Prescription only
Prevents and treats malaria, and also treats a type of bowel infection.

Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people.

Calms down your immune system.

Rituxan (Rituximab) is effective for treating multiple types of cancer and arthritis. That said, you'll need to watch for possibly serious side effects, especially infusion reactions.

Upsides
  • chloroquine is generally safe to use during pregnancy and for children.
  • You can take chloroquine with or without food.
  • Treats leukemia, lymphoma, and blood vessel inflammation.
  • Also treats moderate to severe rheumatoid arthritis that hasn't responded to anti-TNF treatment (but you'll need to take methotrexate too).
  • The chance of having a reaction to the infusion is highest during your first dose, but the risk decreases each time you get Rituxan (Rituximab). It usually happens within 30 minutes to 2 hours after starting the infusion.
  • Rituxan (Rituximab) is a targeted therapy that works differently than chemotherapy. Both work well when they're taken together, especially when treating CLL and NHL.
Downsides
  • chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before.
  • chloroquine is only effective against malaria from certain areas of the world.
  • chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.
  • Only your doctor or other trained medical staff can administer Rituxan (Rituximab), so you'll need to go into an office or clinic for every dose.
  • Not the best choice if you have heart problems.
  • Rituxan (Rituximab) can stay in your body for up to 6 months after you complete treatment. Men and women who are able to have children need to use birth control for up to one year after finishing Rituxan (Rituximab).
  • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
Used for
Dosage forms
  • Pill
  • Infusion (IV)
Price
No pricing information available
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Reviews
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Side effects
The chloroquine FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Any infection
    62%
  • Infusion reaction
    12%
  • Any serious infection
    11%
  • Cardiac side effect
    2%
See more detailed side effects
Risks and risk factors
  • Heart problems
    • Heart problems
  • Muscle weakness
    • Long-term use
  • Low blood counts
    • G6PD (glucose-6-phosphate dehydrogenase) deficiency
  • Eye injury
    • Taking high dose of chloroquine
    • Long-term use
    • Taking tamoxifen
    • Low body weight
    • Kidney problems
  • Liver damage
    • Taking other drugs that affect the liver
    • Alcoholism
    • Liver conditions
  • Hearing damage
    • History of hearing problems
See more detailed risks and warnings
  • Serious allergic reactions
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system
  • Nervous system effects
    • Taking Rituxan (Rituximab) with immunosuppressant drugs (if using for RA)
    • Taking Rituxan (Rituximab) with chemotherapy (if using for NHL or CLL
    • Stem cell transplant
  • Skin and mouth reactions
  • Kidney injury
    • Taking Rituxan (Rituximab) for Non-Hodgkin's Lymphoma (NHL)
    • Rapidly growing tumors
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Gastrointestinal problems
    • Start of therapy with Rituxan (Rituximab)
  • Blood problems
See more detailed risks and warnings