Compare chloroquine vs. Rituxan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aralen Phosphate
(Chloroquine)

Rituxan
(Rituximab)

Coming soon.Calms down your immune system. Rituxan (Rituximab) is effective for treating multiple types of cancer and arthritis. That said, you'll need to watch for possibly serious side effects, especially infusion reactions.
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Reviews & ratings
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Side effects
chloroquineRituxan

We haven’t found good data for chloroquine side effects.

FDA side effect reports for chloroquine »
  • Low blood phosphate 11%
  • Acute infusion reactions 8%
  • Cardiac side effect 1%
More Rituxan side effects »
How it works
chloroquineRituxan
Coming soon.Rituxan (Rituximab) is a monoclonal antibody. It targets a specific protein on white blood cells that makes it easier for your immune system to find and destroy cancerous cells. It also relieves symptoms and slows the progression of Rheumatoid Arthritis.
Type of medication
chloroquineRituxan
Coming soon.
Immunosuppressant
Immunomodulator
Antirheumatic
Biological response modifier
Anticancer
Biological response modifier
Prescription only
Available as
chloroquineRituxan
  • Pill
  • Infusion (IV)
Used for (click to learn more)
chloroquineRituxan
  • Malaria Malaria; Prophylaxis Non-intestinal amebic infection
Risk factors for serious side effects
chloroquineRituxan
Coming soon.
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system
    • Taking Rituxan (Rituximab) with immunosuppressant drugs (if using for RA)
    • Taking Rituxan (Rituximab) with chemotherapy (if using for NHL or CLL
    • Stem cell transplant
      • Taking Rituxan (Rituximab) for Non-Hodgkin's Lymphoma (NHL)
      • Rapidly growing tumors
      • History of heart problems
      • Drug interactions
      • Start of therapy with Rituxan (Rituximab)
        Detailed Rituxan (Rituximab) risks & warnings »
        Pregnancy category
        chloroquineRituxan
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        Alcohol
        No specific alcohol-related info.No specific alcohol-related info.
        Food
        No specific food-related info.No specific food-related info.
        Kidneys and liver
        No specific kidneys and liver-related info.
        • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
        • Tumor lysis syndrome (TLS) happens when cancer cells are broken down very quickly and damage the kidneys. The damage can be so bad that people need dialysis. If you're taking Rituxan (Rituximab) for a cancer condition your doctor can give you medicines and take measures to prevent this reaction.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        No specific sleep-related info.No specific sleep-related info.
        Weight
        No specific weight-related info.
        • Rituxan (Rituximab) can increase your risk of serious or life-threatening bacterial, fungal and viral infections including sepsis. In some cases infections can be reactivated from an inactive virus in your body like tuberculosis (TB) or hepatitis B virus (HBV). You may need to take medicine for TB before you can begin taking Rituxan (Rituximab). If you develop symptoms of cough, fever, chills, muscle aches, feel very tired, or you notice dark urine, yellowing of skin/eyes, appetite/weight loss, vomiting, change in stool color, stomach discomfort, and skin rash, tell your doctor and get medical care right away.
        Upsides and benefits
        chloroquineRituxan
        Coming soon.
        • Treats leukemia, lymphoma, and blood vessel inflammation.
        • Also treats moderate to severe rheumatoid arthritis that hasn't responded to anti-TNF treatment (but you'll need to take methotrexate too).
        • The chance of having a reaction to the infusion is highest during your first dose, but the risk decreases each time you get Rituxan (Rituximab). It usually happens within 30 minutes to 2 hours after starting the infusion.
        • Rituxan (Rituximab) is a targeted therapy that works differently than chemotherapy. Both work well when they're taken together, especially when treating CLL and NHL.
        Downsides and risks
        chloroquineRituxan
        Coming soon.
        • Only your doctor or other trained medical staff can administer Rituxan (Rituximab), so you'll need to go into an office or clinic for every dose.
        • Not the best choice if you have heart problems.
        • Rituxan (Rituximab) can stay in your body for up to 6 months after you complete treatment. Men and women who are able to have children need to use birth control for up to one year after finishing Rituxan (Rituximab).
        • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
        Tips from our pharmacists for people taking the medication
        chloroquineRituxan
        Coming soon.
        • Rituxan (Rituximab) is given as an IV infusion by trained medical staff in a clinic or hospital.
        • You'll need to be monitored in the clinic in case you have a serious or life-threatening reaction during the infusion, but you can take other medications that'll lower your risk of this happening.
        • It's very important that you read the Medication Guide before you start taking Rituxan (Rituximab).
        • Rituxan (Rituximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, a cough that doesn't go away, or flu-like symptoms.
        • Use effective birth control while you're taking Rituxan (Rituximab) and for 12 months after you finish treatment.
        • Don't get live vaccines while you're taking Rituxan (Rituximab).
        Learn more
        More about chloroquineSide effectsFDA package insert
        More about RituxanSide effectsReviews & ratingsAlternativesFDA package insert