Compare chlorpromazine vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Chlorpromazine

Abilify
(Aripiprazole)

Coming soon.Helps control your thoughts and mood. Abilify (Aripiprazole) is good for treating psychosis and mania, and can help with depression. Less likely to cause side effects than any other antipsychotic, but has a risk of suicidal thoughts for people age 24 and younger.
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Reviews & ratings
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Reviews for Abilify (Aripiprazole)
42%
+42% vs. Chlorpromazine
38%
+38% vs. Chlorpromazine
35%
35% vs. Chlorpromazine
Side effects
chlorpromazineAbilify

We haven’t found good data for chlorpromazine side effects.

FDA side effect reports for chlorpromazine »
  • Drowsiness 20%
  • Extrapyramidal disorder 17%
  • Relaxation or sleepiness 17%
  • Fatigue 15%
  • Restlessness 9%
  • Fever 8%
  • Vomiting 7%
  • Decreased appetite 5%
  • Excessive saliva 5%
  • Sleep difficulty 5%
More Abilify side effects »
How it works
chlorpromazineAbilify
Coming soon.Abilify (Aripiprazole) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.
Type of medication
chlorpromazineAbilify
Coming soon.
Antipsychotic
Atypical
Prescription only
Available as
chlorpromazineAbilify
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Used for (click to learn more)
chlorpromazineAbilify
  • Acute intermittent porphyria Apprehension
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about ChlorpromazineThe free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Abilify (Aripiprazole)
Risk factors for serious side effects
chlorpromazineAbilify
Coming soon.
  • Elderly patients with dementia
  • Age 24 years or younger
      • History of heart problems
      • Drug interactions
        • People with diabetes
        • People with high cholesterol
        • People with diabetes
        • Alcohol
        • Taking other medicines that make you less alert
          • Phenylketonuria (PKU)
          Detailed Abilify (Aripiprazole) risks & warnings »
          Pregnancy category
          chlorpromazineAbilify
          NFDA pregnancy category (Unknown)

          The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.
          • Abilify (Aripiprazole) can increase your blood sugar and cholesterol. However, Abilify (Aripiprazole) is the least likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          • Abilify (Aripiprazole) can cause you to gain weight. Abilify (Aripiprazole) is the least likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.
          • Makes you energized. Take in the morning to avoid difficulty sleeping.
          Weight
          No specific weight-related info.
          • Least likely antipsychotic to cause weight gain.
          • Abilify (Aripiprazole) can cause you to gain weight. Abilify (Aripiprazole) is the least likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          Upsides and benefits
          chlorpromazineAbilify
          Coming soon.
          • Effective at relieving psychotic symptoms and manic episodes. All antipsychotic medicines are about equally effective.
          • More energizing than other antipsychotics.
          • Fewer side effects than any other antipsychotics.
          • Least likely antipsychotic to cause weight gain.
          • Less likely to cause heart problems compared to some antipsychotics.
          • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
          • Available as a generic, which is cheaper.
          Downsides and risks
          chlorpromazineAbilify
          Coming soon.
          • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
          • You might need routine blood tests to check how the medicine is affecting your body.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          Tips from our pharmacists for people taking the medication
          chlorpromazineAbilify
          Coming soon.
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • Makes you energized. Take in the morning to avoid difficulty sleeping.
          • For the first week, avoid activities that require you to be alert.
          • May worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          Learn more
          More about chlorpromazineSide effectsFDA package insert
          More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert