Compare Chlorpromazine vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Chlorpromazine

Abilify
(Aripiprazole)

Coming soon.Helps control your thoughts and mood. Abilify (Aripiprazole) is good for treating psychosis and mania, and can help with depression. Less likely to cause side effects than any other antipsychotic, but has a risk of suicidal thoughts for people age 24 and younger.
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Reviews & ratings
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Have you used Chlorpromazine?
Worth itNot sureNot worth it
Reviews for Abilify (Aripiprazole)
44%
+44% better vs. Chlorpromazine
40%
+40% better vs. Chlorpromazine
34%
-34% worse vs. Chlorpromazine
252 reviews
Have you used Abilify (Aripiprazole)?
Worth itNot sureNot worth it
Side effects
ChlorpromazineAbilify

We haven’t found good data for Chlorpromazine side effects.

FDA side effect reports for Chlorpromazine »
  • Headache 4%
  • Agitation 2%
  • Sleep difficulty 5%
  • Anxiety 4%
  • Nausea 4%
  • Restlessness 9%
  • Constipation 4%
  • Vomiting 5%
  • Dizziness 3%
  • Indigestion 2%
More Abilify side effects »
How it works
ChlorpromazineAbilify
Coming soon.Abilify (Aripiprazole) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.
Type of medication
ChlorpromazineAbilify
Prescription only
Available as
ChlorpromazineAbilify
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Used for
ChlorpromazineAbilify
  • Acute Intermittent Porphyria Apprehension
Risk factors for serious side effects
ChlorpromazineAbilify
Coming soon.
  • Elderly patients with dementia
  • Age 24 years or younger
      • History of heart problems
      • Drug interactions
        • People with diabetes
        • People with high cholesterol
        • People with diabetes
        • Alcohol
        • Taking other medicines that make you less alert
          • Phenylketonuria (PKU)
          Detailed Abilify (Aripiprazole) risks & warnings »
          Pregnancy

          The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Weight
          ChlorpromazineAbilify
          No weight related info.
          • Least likely antipsychotic to cause weight gain.
          • Abilify (Aripiprazole) can cause you to gain weight. Abilify (Aripiprazole) is the least likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
          Upsides and benefits
          ChlorpromazineAbilify
          Coming soon
          • Effective at relieving psychotic symptoms and manic episodes. All antipsychotic medicines are about equally effective.
          • More energizing than other antipsychotics.
          • Fewer side effects than any other antipsychotics.
          • Least likely antipsychotic to cause weight gain.
          • Less likely to cause heart problems compared to some antipsychotics.
          • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
          • Available as a generic, which is cheaper.
          Downsides and risks
          ChlorpromazineAbilify
          Coming soon
          • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
          • You might need routine blood tests to check how the medicine is affecting your body.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          Tips from our pharmacists for people taking the medication
          ChlorpromazineAbilify
          Coming soon
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • Makes you energized. Take in the morning to avoid difficulty sleeping.
          • For the first week, avoid activities that require you to be alert.
          • May worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          Learn more
          More about ChlorpromazineSide effectsFDA package insert
          Have you used Chlorpromazine?
          Worth itNot sureNot worth it
          More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Abilify (Aripiprazole)?
          Worth itNot sureNot worth it