Compare chlorpromazine vs. fluphenazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Thorazine (chlorpromazine)

Prescription only

Prolixin (fluphenazine)

Prescription only
Stabilizes your mood.

Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.

Treats schizophrenia and psychosis.

Prolixin (fluphenazine) can stabilize your mood. It is used to find the right dose for you before moving to a long-acting injection.

Upsides
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
  • Good at stabilizing your mood.
  • Available in several oral and injectable forms, including a long-acting injection that is taken less frequently.
Downsides
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can make it difficult for you to control your movements if you've been on Prolixin (fluphenazine) for a while.
Used for
Dosage forms
  • Pill
  • Injection
  • Pill
  • Liquid
  • Injection
Price
Lowest price near you
$126.94
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Lowest price near you
$15.99
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Reviews
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Side effects
The Thorazine (chlorpromazine) FDA package insert doesn’t have numbers about how common side effects are.
The Prolixin (fluphenazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased risk of death

    People over 65 with dementia and psychosis

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

  • Breathing problems

    Asthma

    ...and 2 more risk factors

  • Heat stroke and dehydration

    Benign prostatic hypertrophy (BPH)

    ...and 2 more risk factors

See more detailed risks and warnings
  • Increased risk of death

    People over 65 with dementia and psychosis

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

See more detailed risks and warnings