Compare chlorpromazine vs. fluphenazine decanoate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

chlorpromazine

fluphenazine decanoate

Stabilizes your mood. Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.Treats schizophrenia or psychosis. Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.
Reviews & ratings
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Have you used Thorazine (chlorpromazine)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it
Side effects
chlorpromazinefluphenazine decanoate

The chlorpromazine FDA package insert doesn’t have numbers about how common side effects are.

More about chlorpromazine side effects »

The fluphenazine decanoate FDA package insert doesn’t have numbers about how common side effects are.

More about fluphenazine decanoate side effects »
How it works
chlorpromazinefluphenazine decanoate
Thorazine (chlorpromazine) is a derivative of phenothiazine, which regulates dopamine levels in your brain to improve your mood.Prolixin Decanoate (fluphenazine decanoate) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.
Type of medication
chlorpromazinefluphenazine decanoate
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
chlorpromazinefluphenazine decanoate
  • Pill
  • Injection
  • Injection
Used for
chlorpromazinefluphenazine decanoate
Risk factors for serious side effects
chlorpromazinefluphenazine decanoate
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
  • Asthma
  • COPD
  • Acute respiratory infections
Detailed Thorazine (chlorpromazine) risks & warnings »
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
Detailed Prolixin Decanoate (fluphenazine decanoate) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
chlorpromazinefluphenazine decanoate
  • Don't combine with alcohol or narcotics because it can cause you to stop breathing.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
Sleep
chlorpromazinefluphenazine decanoate
  • Can make you very sleepy so don't drive or do anything that requires concentration until you know how it affects you.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Upsides and benefits
chlorpromazinefluphenazine decanoate
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
Downsides and risks
chlorpromazinefluphenazine decanoate
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
Tips from our pharmacists for people taking the medication
chlorpromazinefluphenazine decanoate
  • Can make you very sleepy so don't drive or do anything that requires concentration until you know how it affects you.
  • Can cause involuntary muscle movements just like other medicines for your mood.
  • Can dry you out and make you more sensitive to the sun.
  • Don't combine with alcohol or narcotics because it can cause you to stop breathing.
  • Cannot be stopped suddenly.
  • Can make you more sensitive to the sun, so wear sunscreen or protective clothing while outside.
  • Can affect how your body regulates your temperature, so drink plenty of liquids especially when you're exercising.
  • Can make it difficult for you to start and stop your movements. Talk to your doctor right away if this happens.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Learn more
More about chlorpromazineSide effectsAlternativesFDA package insert
Have you used Thorazine (chlorpromazine)?
Worth itNot sureNot worth it
More about fluphenazine decanoateSide effectsAlternativesFDA package insert
Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it