Compare chlorpromazine vs. Risperdal

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Chlorpromazine

Risperdal
(Risperidone)

Coming soon.Helps control your thoughts and mood. Risperdal (Risperidone) is good for treating psychosis, mania, and irritability. Among newer antipsychotic medicines, more likely to cause side effects, especially weight gain and hormone problems.
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Reviews & ratings
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Reviews for Risperdal (Risperidone)
48%
+48% vs. Chlorpromazine
41%
+41% vs. Chlorpromazine
48%
48% vs. Chlorpromazine
Side effects
chlorpromazineRisperdal

We haven’t found good data for chlorpromazine side effects.

FDA side effect reports for chlorpromazine »
  • Relaxation or sleepiness 48%
  • Increased appetite 29%
  • Fatigue 22%
  • Parkinsonism 17%
  • Constipation 11%
  • Dizziness 11%
  • Abdominal pain upper 11%
  • Common cold 10%
  • Nausea 9%
  • Indigestion 8%
More Risperdal side effects »
How it works
chlorpromazineRisperdal
Coming soon.Risperdal (Risperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.
Type of medication
chlorpromazineRisperdal
Coming soon.
Antipsychotic
Atypical
Prescription only
Available as
chlorpromazineRisperdal
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Used for (click to learn more)
chlorpromazineRisperdal
  • Acute intermittent porphyria Apprehension
Risk factors for serious side effects
chlorpromazineRisperdal
Coming soon.
  • Elderly patients with dementia
      • History of heart problems
      • Drug interactions
        • People with diabetes
        • People with high cholesterol
        • People with diabetes
        • Alcohol
        • Taking other medicines that make you less alert
          Detailed Risperdal (Risperidone) risks & warnings »
          Pregnancy category
          chlorpromazineRisperdal
          NFDA pregnancy category (Unknown)

          The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.
          • Risperdal (Risperidone) can increase your blood sugar and cholesterol. Exercise and eat healthy food to lower your risk.
          • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.
          • Can cause dizziness and drowsiness.
          Weight
          No specific weight-related info.
          • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
          Upsides and benefits
          chlorpromazineRisperdal
          Coming soon.
          • Effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior.
          • Lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
          • Antipsychotic medicines are all about equally effective.
          • Less likely to cause heart problems than some antipsychotics.
          Downsides and risks
          chlorpromazineRisperdal
          Coming soon.
          • Mild to moderate risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • Compared to other antipsychotics, higher risk of hormone problems that cause nipples to leak and male breasts to grow abnormally large.
          • You might need routine blood tests to check how the medicine is affecting your body.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          Tips from our pharmacists for people taking the medication
          chlorpromazineRisperdal
          Coming soon.
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • Can cause dizziness and drowsiness.
          • For the first week, avoid activities that require you to be alert.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          Learn more
          More about chlorpromazineSide effectsFDA package insert
          More about RisperdalSide effectsReviews & ratingsAlternativesFDA package insert