Compare chlorpromazine vs. scopolamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Stabilizes your mood.

Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.

Prevents nausea and vomiting.

Transderm-Scop (scopolamine) is a low-hassle patch that works well to prevent nausea and vomiting, but it takes several hours to work.

3.9/ 5 average rating with 26 reviewsforscopolamine
Upsides
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
  • Transderm-Scop (scopolamine) is well tolerated.
  • Prevents nausea for 3 days.
  • Because Transderm-Scop (scopolamine) is a skin patch, it's a good alternative to stopping nausea and vomiting if you're not able to swallow pills.
Downsides
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
  • Can only be used for prevention of nausea and vomiting. It can't stop nausea or vomiting that's already happening.
  • The side effects can be worse if you are 65 and older.
  • You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
  • You're more likely to have heat stroke or feel dehydrated.
  • It takes a few hours for Transderm-Scop (scopolamine) to kick in, so you have to remember to take it beforehand.
Used for
Dosage forms
  • Pill
  • Injection
  • Patch
Price
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Reviews
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26 reviews so far
73%
saidit'sworth it
58%
saiditworked well
19%
saidit'sa big hassle

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Side effects
The Thorazine (chlorpromazine) FDA package insert doesn’t have numbers about how common side effects are.
The Transderm-Scop (scopolamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased risk of death
    • People over 65 with dementia and psychosis
  • Difficulty controlling movements
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Breathing problems
    • Asthma
    • COPD
    • Acute respiratory infections
  • Heat stroke and dehydration
    • Benign prostatic hypertrophy (BPH)
    • Urinary retention
    • Decreased movement in the intestines
See more detailed risks and warnings
  • Increased pressure in the eyes
    • Open angle glaucoma
  • Worsening stomach, bowel, or bladder blockages
    • Blockages in the stomach, bowels or bladder
  • Skin burns
    • MRI examination
  • Heat stroke
  • Worsening seizures or psychosis
    • History of seizures
    • History of psychosis
  • Sleepiness and dizziness
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings