Compare chlorpromazine vs. Scopolamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Thorazine
(chlorpromazine)

Transderm-Scop
(scopolamine)

Stabilizes your mood. Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.Helps you feel less queasy. Transderm-Scop (Scopolamine) works well to prevent nausea and vomiting and the patch is low-hassle, but it takes about 4 hours to kick in.
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Coupons for chlorpromazine
Best available price for 60 (25mg) tablets of chlorpromazine
Coupons for Scopolamine
Best available price for 4 (1.5mg) patches of scopolamine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Thorazine (chlorpromazine)
Not enough review data. Review it!
of people (All ages) say Thorazine (chlorpromazine) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Thorazine (chlorpromazine)?
Worth itNot sureNot worth it
Reviews for Transderm-Scop (scopolamine)
73%
+73% better vs. Thorazine (chlorpromazine)
58%
+58% better vs. Thorazine (chlorpromazine)
19%
-19% worse vs. Thorazine (chlorpromazine)
Have you used Transderm-Scop (scopolamine)?
Worth itNot sureNot worth it
Side effects
chlorpromazineScopolamine

The chlorpromazine FDA package insert doesn’t have numbers about how common side effects are.

More about chlorpromazine side effects »
  • Dry mouth 66%
  • Dizziness 17%
  • Any side effect 10%
  • Drowsiness 4%
  • Agitation 2%
  • Visual impairment 2%
  • Confusion 1%
  • Dilated pupil 4%
  • Sore throat 1%
More Scopolamine side effects »
How it works
chlorpromazineScopolamine
Thorazine (chlorpromazine) is a derivative of phenothiazine, which regulates dopamine levels in your brain to improve your mood.Transderm-Scop (Scopolamine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.
Type of medication
chlorpromazineScopolamine
Prescription only
Prescription only
Available as
chlorpromazineScopolamine
  • Pill
  • Injection
  • Patch
Used for
chlorpromazineScopolamine
Risk factors for serious side effects
chlorpromazineScopolamine
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
  • Asthma
  • COPD
  • Acute respiratory infections
Detailed Thorazine (chlorpromazine) risks & warnings »
  • Glaucoma
  • Doing an MRI
  • History of seizures
  • History of psychosis
  • Taking with alcohol
Detailed Transderm-Scop (scopolamine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
chlorpromazineScopolamine
  • Don't combine with alcohol or narcotics because it can cause you to stop breathing.
  • You have to avoid alcohol while on the medication.
  • Don't drink alcohol if you have to use the patch.
Sleep
chlorpromazineScopolamine
  • Can make you very sleepy so don't drive or do anything that requires concentration until you know how it affects you.
No sleep related info.
Upsides and benefits
chlorpromazineScopolamine
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
  • Even though there's no generic version available, it's inexpensive.
  • Placed on the skin so it can be used if you can't keep anything in your stomach.
  • Can be used for long-term control of nausea and vomiting since it's only placed on every 3 days.
Downsides and risks
chlorpromazineScopolamine
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
  • Can only be used to prevent nausea and vomiting, not to treat it if it's already happening.
  • Takes about 4 hours for it to start working.
  • You have to avoid alcohol while on the medication.
Tips from our pharmacists for people taking the medication
chlorpromazineScopolamine
  • Can make you very sleepy so don't drive or do anything that requires concentration until you know how it affects you.
  • Can cause involuntary muscle movements just like other medicines for your mood.
  • Can dry you out and make you more sensitive to the sun.
  • Don't combine with alcohol or narcotics because it can cause you to stop breathing.
  • Cannot be stopped suddenly.
  • Wash your hands after you place the patch.
  • Don't touch or rub your eyes after putting on the patch before washing your hands.
  • Can cause blurry vision and sleepiness.
  • Take the patch off if you have to do an MRI.
  • Don't drink alcohol if you have to use the patch.
  • Place it on a few hours before if you know you'll be in a place where you might get motion sickness.
Learn more
More about chlorpromazineSide effectsAlternativesFDA package insert
Have you used Thorazine (chlorpromazine)?
Worth itNot sureNot worth it
More about ScopolamineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Transderm-Scop (scopolamine)?
Worth itNot sureNot worth it