Compare Chlorpromazine vs. Seroquel

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Chlorpromazine

Seroquel
(Quetiapine)

Coming soon.Helps control your thoughts and mood. Seroquel (Quetiapine) is good for treating psychosis and mania. Fewer side effects than most antipsychotics, but might be less effective for people over age 40 with schizophrenia.
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Reviews & ratings
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Have you used Chlorpromazine?
Worth itNot sureNot worth it
Reviews for Seroquel (Quetiapine)
56%
+56% vs. Chlorpromazine
50%
+50% vs. Chlorpromazine
27%
27% vs. Chlorpromazine
250 reviews
Have you used Seroquel (Quetiapine)?
Worth itNot sureNot worth it
Side effects
ChlorpromazineSeroquel

We haven’t found good data for Chlorpromazine side effects.

FDA side effect reports for Chlorpromazine »
  • Drowsiness 43%
  • Dizziness 17%
  • Fatigue 10%
  • Increased appetite 9%
  • Nausea 6%
  • Vomiting 5%
  • Nasal congestion 4%
  • Fever 3%
  • Joint pain 3%
  • Stomach discomfort 3%
More Seroquel side effects »
How it works
ChlorpromazineSeroquel
Coming soon.Seroquel (Quetiapine) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.
Type of medication
ChlorpromazineSeroquel
Coming soon.
Antipsychotic
Atypical
Prescription only
Available as
ChlorpromazineSeroquel
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
ChlorpromazineSeroquel
  • Acute intermittent porphyria Apprehension
Risk factors for serious side effects
ChlorpromazineSeroquel
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
ChlorpromazineSeroquel
No food related info.
  • Seroquel (Quetiapine) can increase your blood sugar and cholesterol. Seroquel (Quetiapine) is more likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Seroquel (Quetiapine) can cause you to gain weight. Seroquel (Quetiapine) is moderately likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
Sleep
ChlorpromazineSeroquel
No sleep related info.
  • Can cause dizziness, drowsiness, and low blood pressure.
Weight
ChlorpromazineSeroquel
No weight related info.
  • Sometimes causes weight gain, sleepiness, and low blood pressure.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Seroquel (Quetiapine) can cause you to gain weight. Seroquel (Quetiapine) is moderately likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
Upsides and benefits
ChlorpromazineSeroquel
Coming soon
  • Effective at relieving psychotic symptoms and manic episodes.
  • Antipsychotic medicines are all about equally effective.
  • Fewer side effects than most antipsychotic medicines.
  • Less likely to cause heart problems compared to some antipsychotics.
  • Compared to other antipsychotics, the least likely to cause Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
Downsides and risks
ChlorpromazineSeroquel
Coming soon
  • In studies, less effective for people over age 40 for schizophrenia.
  • Sometimes causes weight gain, sleepiness, and low blood pressure.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
Tips from our pharmacists for people taking the medication
ChlorpromazineSeroquel
Coming soon
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Can cause dizziness, drowsiness, and low blood pressure.
  • For the first week, avoid activities that require you to be alert.
  • May cause weight gain and worsen cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people with dementia shouldn't take it.
Learn more
More about ChlorpromazineSide effectsFDA package insert
Have you used Chlorpromazine?
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More about SeroquelSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Seroquel (Quetiapine)?
Worth itNot sureNot worth it