Compare chlorpromazine vs. thioridazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Thorazine (chlorpromazine)

Prescription only

Mellaril (thioridazine)

Prescription only
Stabilizes your mood.

Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.

Treats schizophrenia.

Taking Mellaril (thioridazine) is one of many options to treat schizophrenia if other medicines haven't worked, but there are some side effects which can be dangerous.

Upsides
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
  • Available in generic.
  • Compared to other similar medicines, Mellaril (thioridazine) is less likely to cause problems controlling your movements.
Downsides
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
  • Mellaril (thioridazine) is only recommended for schizophrenia if other medicines haven't worked because the side effects can be very dangerous.
  • You have to take Mellaril (thioridazine) numerous times a day which can make it hard to remember.
  • Mellaril (thioridazine) can interfere with your heartbeat, so your doctor might have you do annual tests with your heart to make sure it's healthy.
Used for
Dosage forms
  • Pill
  • Injection
  • Pill
Price
Lowest price near you
$122.62
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Lowest price near you
$23.72
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Side effects
The Thorazine (chlorpromazine) FDA package insert doesn’t have numbers about how common side effects are.
The Mellaril (thioridazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased risk of death

    People over 65 with dementia and psychosis

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

  • Breathing problems

    Asthma

    ...and 2 more risk factors

  • Heat stroke and dehydration

    Benign prostatic hypertrophy (BPH)

    ...and 2 more risk factors

See more detailed risks and warnings
  • Problems with the heartbeat

    History of heartbeat problems

    ...and 2 more risk factors

  • Increased risk of death in elderly people with dementia

    People older than 65 years with dementia and psychosis

  • Difficulty controlling movements

    Long-term use of Mellaril (thioridazine)

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

  • Sleepiness and risk of falls

    Drinking alcohol or taking narcotics

  • Decreased white blood cells

    History of low white blood cells

See more detailed risks and warnings