Compare chlorpromazine vs. Zyprexa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Thorazine (chlorpromazine)

Prescription only

Zyprexa (olanzapine)

Prescription only
Stabilizes your mood.

Thorazine (chlorpromazine) has more side effects than other medicines like it. It is most useful during psychotic episodes because it slows you down quickly.

Helps control your thoughts and mood.

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.

5.1/ 7 average rating with 68 reviewsforZyprexa
Upsides
  • Acts fast to slow you down during a psychotic episode.
  • Can also be used for nausea or migraines.
  • Safe for use in children as young as 6 months.
  • Comes in a sugar-coated pill for easy administration.
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
Downsides
  • Has more side effects than other medicines like it.
  • Can affect how your other medicines work.
  • Makes you more sensitive to the sun.
  • Can make you dizzy or lightheaded, especially when injected.
  • Cannot be stopped right away.
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
Used for
Dosage forms
  • Pill
  • Injection
  • Pill
  • Dissolving tablet
  • Injection
Price
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$126.94
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$12.05
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Reviews
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68 
41%
think this treatment is worth it
51%
think this treatment works well
51%
think this treatment is a hassle

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Side effects
The Thorazine (chlorpromazine) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Drowsiness
    48%
  • Weight gain
    28%
  • Increased appetite
    28%
  • Headache
    17%
  • Fatigue
    14%
  • Dizziness
    7%
  • Dry Mouth
    7%
  • Abdominal pain
    6%
  • Pain in extremity
    5%
See more detailed side effects
Risks and warnings
  • Increased risk of death

    People over 65 with dementia and psychosis

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

  • Breathing problems

    Asthma

    ...and 2 more risk factors

  • Heat stroke and dehydration

    Benign prostatic hypertrophy (BPH)

    ...and 2 more risk factors

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Higher blood sugar, high cholesterol, and weight gain

    People with diabetes

    ...and 1 more risk factors

See more detailed risks and warnings